Mice naturally form social hierarchies, and their experiences as subordinate or dominant mice inform future behavioural strategies. To better understand the neural bases of social dominance, we investigated hippocampal gene and protein expression of histone deacetylase 2 (HDAC2), an epigenetic regulator that decreases expression of synaptic plasticity genes and reduces excitatory synaptic function. Hdac2 in hippocampus was associated with social status. The gene for a closely related histone deacetylase (Hdac1), and HDAC2 protein expression, were not associated with social rank in hippocampus. These findings suggest that Hdac2 expression in hippocampus is distinctly linked with social status.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.physbeh.2023.114406 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The Role of Race/Ethnicity on the Association between Neighborhood Deprivation and Breast Cancer Outcomes among Kentucky Breast Cancer Patients years 2010-2022.
Cancer Epidemiol Biomarkers Prev
January 2025
University of Kentucky, Lexington, KY, United States.
Background: Kentucky is within the top five leading states for breast mortality nationwide. This study investigates the association between neighborhood socioeconomic disadvantage and breast cancer outcomes, including surgical treatment, radiation therapy, chemotherapy, and survival, and how associations vary by race and ethnicity in Kentucky.
Methods: We conducted a retrospective cohort analysis using data from the Kentucky Cancer Registry (KCR) for breast cancer patients diagnosed between 2010 and 2017, with follow-up through December 31, 2022.
Neighborhood Socioeconomic Status and Breastfeeding Initiation and Duration Among Primiparous Black Women.
Breastfeed Med
January 2025
Slone Epidemiology Center, Boston University, Boston, Massachusetts, USA.
Social determinants of health account for racial inequities in breastfeeding rates in the United States. There is a gap in the role of neighborhood socioeconomic status (NSES) as it relates to breastfeeding disparities. Using longitudinal data from the Black Women's Health Study, we assessed associations of NSES with breastfeeding initiation and duration in a cohort of primiparous U.
View Article and Find Full Text PDFPerceived Burnout Among Underrepresented Minority Physician Assistant/Associate Educators in the United States.
J Physician Assist Educ
January 2025
Daytheon Sturges, PhD, MPAS, PA-C, MCHES, is an associate professor, vice chair-Justice, Equity, Diversity, & Inclusion (JEDI), Department of Family Medicine. He is also an associate program director-Regional Affairs and JEDI, MEDEX Northwest at School of Medicine, University of Washington, Seattle, WA.
Introduction: There is a keen interest regarding burnout in academic medicine with an existing need for more studies. The priority population were underrepresented physician assistant/associate (PA) educators in the United States. The purpose was to determine external/internal contributors leading to perceived burnout; investigate whether primary/secondary appraisal inform coping strategies; and determine whether there was an existing relationship between demographic factors and emotional exhaustion (EE).
View Article and Find Full Text PDFGesture screening in young infants: Highly sensitive to risk factors for communication delay.
Int J Lang Commun Disord
January 2025
Language Development Department, Max Planck Institute for Psycholinguistics, Nijmegen, The Netherlands.
Introduction: Children's early language and communication skills are efficiently measured using parent report, for example, communicative development inventories (CDIs). These have scalable potential to determine risk of later language delay, and associations between delay and risk factors such as prematurity and poverty. However, there may be measurement difficulties in parent reports, including anomalous directions of association between child age/socioeconomic status and reported language.
View Article and Find Full Text PDFAssociation Between Oral Health Status and DMFT Index with Cognitive Dysfunction in Community-Dwelling Older Adults with Type 2 Diabetes: A Cross-Sectional Study.
Exp Aging Res
January 2025
Dental Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
Objective: Cognitive dysfunction is a significant issue in old age and can cause many problems in older adults, especially those with diabetes. This study aimed to investigate the association between oral health status and DMFT index with cognitive dysfunction in community-dwelling older adults with T2D (type 2 diabetes).
Methods: This was a cross-sectional study that included 245 older people aged 60 years and older with T2D, visiting healthcare centers in north of Iran, using the cluster sampling method.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!