AI Article Synopsis
- Vitamin B is linked to cognitive performance, but its effectiveness may depend on the presence of other nutrients like folate and adherence to the Mediterranean diet.
- A study involving 170 older participants showed a strong correlation between serum vitamin B levels and memory function among those with high adherence to the Mediterranean diet, while the link was weaker for those with lower adherence.
- High adherence to the Mediterranean diet was associated with increased serum folate levels, indicating that dietary patterns influence cognitive function beyond just vitamin B intake.
Article Abstract
Background & Aims: Vitamin B plays a crucial role in cognition, but its effect might be regulated by the presence of other micronutrients, such as folate. The aim was to evaluate the effects of vitamin B on cognitive performance according to adherence to the Mediterranean diet, and whether the Mediterranean diet also results in increased folate or vitamin B12 levels.
Methods: This is a cohort study nested in a randomized controlled clinical trial performed in Hospital Clinic in Barcelona, Spain. A total of 170 participants of the PREDIMED trial (Barcelona - Hospital Clinic site) aged 55-80 years at high cardiovascular risk were included. Adherence to the Mediterranean diet was assessed using a validated 14-item questionnaire, memory function was evaluated with a battery of neuropsychological tests and serum vitamin B and folate were determined using an automated electrochemiluminiscence immunoassay system.
Results: In the multivariable adjusted linear regression model, serum vitamin B concentration presented a significant correlation with memory function (r = 0.57; P = 0.028) in participants with high adherence to the Mediterranean diet whereas the correlation was weak and inverse for those who presented a low adherence to the Mediterranean diet (r = 0.37, P = 0.731). Mediterranean diet adherence showed a positive association with serum folate, but not with serum vitamin B.
Conclusions: In an older Mediterranean population at high cardiovascular risk, changes in serum vitamin B correlate with better memory function only in the context of a high adherence to the Mediterranean pattern, suggesting that the effects of vitamin B goes further than a mere nutritional requirement.
Institutional Review Board Statement: The study was conducted according to the guidelines of the Declaration of Helsinki and was approved by the Institutional Review Board of the 11 participating centres. The study was registered with the International Standard Randomized Controlled Trial Number (ISRCTN) 35739639 (https://www.isrctn.com/ISRCTN35739639).
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.clnu.2023.10.025 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Towards a Thriving Workplace: A Feasibility Study on Mindfulness and the Mediterranean Lifestyle for Corporate Wellness.
Healthcare (Basel)
December 2024
Laboratory of Nutritional and Public Health, Department of Food Science and Nutrition, University of the Aegean, 81400 Myrina, Greece.
This study explores the potential of integrating mindfulness and the Mediterranean lifestyle into corporate wellness programs to enhance workplace well-being. A survey of 485 employees from Greece and Cyprus examined how mindfulness, resilience, adherence to the Mediterranean lifestyle, and work ability are connected. Pearson correlation analysis showed statistically significant positive relationships between mindfulness, resilience, and work ability ( < 0.
View Article and Find Full Text PDFDevelopment and evaluation of a free e-learning program on dementia risk reduction for the general public: A pre-post study.
J Alzheimers Dis
January 2025
Alzheimer Centrum Limburg, Mental Health and Neuroscience Research Institute (MHeNs), Department of Psychiatry and Neuropsychology, Maastricht University, Maastricht, Netherlands.
Background: There is consistent evidence for the contribution of modifiable risk factors to dementia risk, offering opportunities for primary prevention. Yet, most individuals are unaware of these opportunities.
Objective: To investigate whether online education about dementia risk reduction may be a low-level means to increase knowledge and support self-management of modifiable dementia risk factors.
The efficacy and feasibility of lifestyle interventions on modifiable cardiovascular disease risk factors among people with inflammatory bowel disease.
Proc Nutr Soc
January 2025
University of Otago, Dunedin, New Zealand.
This review aims to highlight the relative importance of cardiovascular disease (CVD) lifestyle-associated risk factors among individuals with inflammatory bowel disease (IBD) and examine the effectiveness of lifestyle interventions to improve these CVD risk factors. Adults with IBD are at higher risk of CVD due to systemic and gut inflammation. Besides that, tobacco smoking, dyslipidaemia, hypertension, obesity, physical inactivity, and poor diet can also increase CVD risk.
View Article and Find Full Text PDFEffect of Plant-Based Diets on Rheumatoid Arthritis: A Systematic Review.
Nutr Rev
December 2024
Department of Nutrition and Dietetics, Kent University, 34406 İstanbul, Türkiye.
Context: Rheumatoid arthritis (RA) is an autoimmune disease that leads to chronic inflammation and joint damage. Various plant-based diets are thought to have effects on RA symptoms and disease activity.
Objective: Relevant literature on the effect of different types of plant-based diets on RA was reviewed.
The Impact of Diet on AD Biomarkers in a Community‐Based Sample.
Alzheimers Dement
December 2024
Columbia University Irving Medical Center, New York, NY, USA
Background: Greater adherence to the Mediterranean Diet (MeDi) is associated with lower risk for cardiovascular disease, slower cognitive decline, and reduced risk for Alzheimer’s Disease (AD). However, its association with AD biomarkers is not well known. We hypothesized that greater MeDi adherence is associated with reduced amyloid and tau PET burden in a community‐based sample of older adults in Northern Manhattan.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!