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[State of digitalization in dermatopathology].

Pathologie (Heidelb)

January 2025

MVZ Dermatopathologie Duisburg Essen GmbH, Essen, Deutschland.

As in general pathology, digitalization is also inexorably making its way into dermatopathology. This article examines the current state of digitalization in German dermatopathology laboratories based on the authors' own experiences, the current study situation, and a survey of members of the Dermatological Histology Working Group (ADH). Experiences with the establishment of a digital laboratory workflow, artificial intelligence (AI)-based assistance systems, and whole slide images (WSI)-based training programs are discussed.

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Background: Portal hypertension (PH) resulting from static and dynamic intrahepatic changes drives liver-related complications even after removing the underlying aetiological factor.

Objective: We investigated the impact of inflammation on the dynamic component of PH during disease regression in animal models of toxin-induced cirrhosis and patients with alcohol-related cirrhosis.

Methods: In mice, cirrhosis was induced via toxin application for 12 weeks followed by toxin-withdrawal allowing for one or 2 weeks of regression.

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Dementia and Video Games: Systematic and Bibliographic Review.

Healthcare (Basel)

November 2024

Stabsstelle für Digitalisierung und Wissensmanagement, Hochschule Hamm-Lippstadt, 59063 Hamm, Germany.

Background/objectives: This systematic and bibliographic review examines publications in the field of dementia and video game research from 2004 to 2023. The main objective is to assess developments and trends in video game technology for dementia care and detection.

Methods: The PubMed database was the primary source for publications.

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[Digitization in the diagnosis and treatment of headache].

MMW Fortschr Med

November 2024

Klinik und Poliklinik für Neurologie, Universitätsklinikum Essen, Hufelandstraße 55, 45147, Essen, Germany.

Article Synopsis
  • Machine learning, especially Natural Language Processing, is increasingly helping to analyze unstructured health data like headache histories.
  • Algorithms can effectively identify patterns and automate the diagnosis of various headache types.
  • Digital tools, such as headache diaries and trigger-analysis apps, are enhancing therapy options, offering scalable non-drug treatments for headaches and migraines.*
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Cyclic Acetals as Expanding Monomers to Reduce Shrinkage.

Angew Chem Int Ed Engl

December 2024

Institute of Applied Synthetic Chemistry, Technische Universität Wien, Getreidemarkt 9/163 MC, 1060, Vienna, Austria.

Polarity-reversal catalysts (PRCs) for hydrogen-atom transfer reactions have been known in radical chemistry for more than 60 years but are rarely described and utilized in the field of photopolymerization up to now. Herein, we present the use of thiols in a unique dual function as thiol-ene click reagents and as polarity-reversal catalyst (PRC) for the radical-mediated redox rearrangements of benzylidene acetals. During the rearrangement reaction, cyclic benzylidene acetals are transformed into benzoate esters leading to a significant volumetric expansion to reduce thermoset shrinkage.

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