Primary Biliary Cholangitis: Pathophysiology.

Clin Liver Dis

Division of Gastroenterology and Hepatology, Toronto Centre for Liver Disease, University of Toronto, 9th Floor Eaton Building, North Wing 219-B, 200 Elizabeth Street, Toronto, Ontario M5G 2C4, Canada. Electronic address:

Published: February 2024

AI Article Synopsis

Article Abstract

Primary biliary cholangitis (PBC) is the most common of the autoimmune liver diseases, in which there is chronic small bile duct inflammation. The pathophysiology of PBC is multifactorial, involving immune dysregulation and damage to biliary epithelial cells, with influences from genetic factors, epigenetics, the gut-liver axis, and environmental exposures.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cld.2023.06.006DOI Listing

Publication Analysis

Top Keywords

primary biliary
8
biliary cholangitis
8
cholangitis pathophysiology
4
pathophysiology primary
4
cholangitis pbc
4
pbc common
4
common autoimmune
4
autoimmune liver
4
liver diseases
4
diseases chronic
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!