Post covid cerebral phaeohyphomycosis by Rhinocladiella mackenziei: An unusual association.

Indian J Med Microbiol

P.D. Hinduja National Hospital and Research Center, Mumbai, India; Department of Neurosurgery and Gamma Knife Radiosurgery, P.D. Hinduja National Hospital and Research Center, Mumbai, 400016, India. Electronic address:

Published: November 2023

AI Article Synopsis

  • Cerebral phaeohyphomycosis (CP) is a serious and rare fungal infection affecting the central nervous system, primarily caused by fungi in the Chaetothyriales order.
  • The infection is linked to very high mortality rates, exceeding 80%, and is associated with poor clinical outcomes.
  • The case study discusses a 65-year-old man who contracted CP due to Rhinocladiella mackenziei after recovering from COVID-19, highlighting the complexities of his treatment.

Article Abstract

Cerebral phaeohyphomycosis (CP) is a rare but a highly morbid fungal infection of the central nervous system caused by the fungi belonging to the order Chaetothyriales, which includes Cladophialophora bantiana, Exophiala dermatitidis, Rhinocladiella mackenziei (RM) etc. This disease is associated with poor clinical outcomes, with reported mortality of over 80%. We present the case of a 65-year gentleman who developed CP secondary to RM infection following COVID-19 and the associated challenges in his medical and surgical management.

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Source
http://dx.doi.org/10.1016/j.ijmmb.2023.100430DOI Listing

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