AI Article Synopsis

  • * A study of 3950 patients showed that 17 had PLSVC; most had prior pulmonary vein isolation (PVI) and many benefited from isolating PLSVC during treatment.
  • * After an average follow-up of about 28 months, about 76.5% of patients were free from AF or atrial tachycardia, suggesting that isolating PLSVC is a promising method to reduce AF recurrence.

Article Abstract

Background: Persistent left superior vena cava (PLSVC) is the most prevalent form of thoracic venous abnormality and can serve as a significant arrhythmogenic source in atrial fibrillation (AF).

Methods And Results: Among the 3950 patients who underwent radiofrequency ablation for AF between September 2014 to April 2020, 17 patients (mean age 59.4 ± 8.0 years, 64.7% male) with PLSVC were identified. Among them, nine patients (52.9%) had a prior history of pulmonary vein isolation (PVI) alone. Eight out of nine patients who experienced AF recurrence underwent PLSVC isolation with or without pulmonary vein (PV) reconnection. For the remaining eight patients (47.1%), PVI plus PLSVC isolation were performed during the index procedure. Ectopy originating from PLSVC was documented in 11 patients (64.7%) and successful PLSVC isolation was achieved in 16 patients (94.1%). After a median follow-up of 28.3 months, freedom from AF/ atrial tachycardia (AT) was observed in 13 patients (76.5%).

Conclusion: Empirical PLSVC isolation beyond PVI appears to be a feasible and safe strategy to prevent AF recurrence in patients with concomitant PLSVC.

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Source
http://dx.doi.org/10.1111/pace.14872DOI Listing

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