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Objective: This study explores whether hyaluronic acid (HA) of different molecular weights and collagen, given their role in tendon extracellular matrix maintenance, have a synergistic effect on human tendon-derived cells, with the aim to improve the treatment of tendinopathy.

Material: Human monocytes (CRL-9855™) and primary Achilles tendon-derived cells.

Treatment: The collagen/HA ratio was based on the formulation of the commercial food supplement TendoGenIAL™.

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Boosting the Actuation Performance of a Dynamic Supramolecular Polyurethane-Urea Elastomer via Kinetic Control.

ACS Appl Mater Interfaces

January 2025

College of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering, Sichuan University, Chengdu 610065, China.

The ongoing soft actuation has accentuated the demand for dielectric elastomers (DEs) capable of large deformation to replace the traditional rigid mechanical apparatus. However, the low actuation strain of DEs considerably limits their practical applications. This work developed high-performance polyurethane-urea (PUU) elastomers featuring large actuation strains utilizing an approach of kinetic control over the microphase separation structure during the fabrication process.

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The large amounts of attention directed towards the commercialization of renewable energy systems have motivated extensive research to develop non-precious-metal-based catalysts for promoting the electrochemical production of H and O from water. Here, we report promising technology, , electrochemical water splitting for OER and HER. This work used a simple hydrothermal method to synthesize a novel CoTe-FeC nanocomposite directly on a stainless-steel substrate.

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The scientific establishment of the Ecological Security Pattern (ESP) is crucial for fostering the synergistic development of ecological and recreational functions, thereby enhancing urban ecological protection, recreational development, and sustainable growth. This study aimed to propose a novel method of constructing ESP considering both ecological and recreational functions, and to reconstruct ESP by weighing the relationship between ecological protection and recreational development. Utilizing Fuzhou City as a case study, a comprehensive application of methodologies including Morphological Spatial Pattern Analysis (MSPA), landscape connectivity analysis, ArcGIS spatial analysis, social network analysis (SNA), and circuit theory is employed to develop both the ESP and the Recreational Spatial Pattern (RSP).

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Co-delivery of astaxanthin using positive synergistic effect from biomaterials: From structural design to functional regulation.

Food Chem

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College of Food Science and Technology, Shanghai Ocean University, Shanghai, China; Shanghai Engineering Research Center of Aquatic-Product Processing and Preservation, Shanghai, China; National Experimental Teaching Demonstration Center for Food Science and Engineering, Shanghai Ocean University, Shanghai, China. Electronic address:

The powerful antioxidant properties of astaxanthin (AST) face two significant challenges: low water solubility and poor chemical stability. To overcome them, extensive research and development efforts have been directed toward creating effective delivery systems. Among them, the positive synergistic effect between biomaterials can be used to refine the design of delivery systems.

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