Computer systems based on motion assessment are promising solutions to support stroke survivors' autonomous rehabilitation exercises. In this regard, researchers keep trying to achieve engaging and low-cost solutions suitable mainly for home use. Aiming to achieve a system with a minimal technical setup, we compare Microsoft Kinect, OpenPose, and MediaPipe skeleton tracking approaches for upper extremity quality of movement assessment after stroke. We determine if classification models assess accurately exercise performance with OpenPose and MediaPipe data against Kinect, using a dataset of 15 stroke survivors. We compute Root Mean Squared Error to determine the alignment of trajectories and kinematic variables. MediaPipe World Landmarks revealed high alignment with Kinect, revealing to be a potential alternative method.
Mechanical unloading causes bone loss, but it remains unclear whether disuse-induced changes to bone microstructure are permanent or can be recovered upon reloading. We examined bone loss and recovery in 17 astronauts using time-lapsed high-resolution peripheral quantitative computed tomography and biochemical markers to determine whether disuse-induced changes are permanent. During 6 months in microgravity, resorption was threefold higher than formation.
Background: Although osteoarthritis (OA) is the most prevalent form of arthritis, there is still no effective treatment capable of combining immunomodulatory effects with cartilage repair. Extracellular vesicles (EVs) represent a promising new generation of cell-free therapies for OA. Blood-derived products, including plasma, are an easily available and abundant source of EVs with anti-inflammatory and regenerative properties.
The importance of optimizing intrathecal drug delivery is highlighted by its potential to improve patient health outcomes. Findings from previous computational studies, based on an individual or a small group, may not be applicable to the wider population due to substantial geometric variability. Our study aims to circumvent this problem by evaluating an individual's cycle-averaged Lagrangian velocity field based on the geometry of their spinal subarachnoid space.
Institute of Orthopaedic Research and Biomechanics, Trauma Research Centre Ulm, Ulm University Medical Centre, Helmholtzstraße 14, 89081, Ulm, Germany.
Scoliosis instrumentation length depends on the type and degree of deformity and the individual preference of the surgeon. This in vitro study aimed to explore effects of increasing instrumentation length on adjacent segment mobility and intervertebral disc loading. Six fresh frozen human spine specimens (C7-sacrum) with entire rib cage from young adult donors (26-45 years) were loaded with pure moments of 5 Nm.
Neurosurgical complications are a rich source for learning, but they are grossly underutilized for the purpose of surgeon education. Details of the complications, which make them all the more powerful as teaching tools, are restricted to morbidity and mortality conferences behind closed doors, and open discussions of the topic are blurred by hypotheticals in order to shield the presenters from medicolegal risks. In this issue of Neurosurgical Focus, 9 neurosurgeons were invited to present complications they encountered along with the details and specific lessons they learned.
