Bromadiolone is still often used in life as a poisonous rodent agent. Bromadiolone poisoning is often manifested as coagulation dysfunction, resulting in organ bleeding, including cerebral hemorrhage, intestinal bleeding, abdominal hemorrhage, etc. At present, no case of intestinal necrosis caused by bromadiolone poisoning have been reported. This article reviewed one case of intestinal necrosis and severe coagulation dysfunction, and finally confirmed bromadiolone poisoning by poison detection. The patient recovered and was discharged after surgery, vitamin K injection, plasma transfusion and other treatment methods.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.3760/cma.j.cn121094-20221201-00567 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Non-adherence with long-term oral vitamin K therapy in acute long-acting anticoagulant rodenticides poisoning: A call for action.
Toxicol Commun
April 2024
Department of Anesthesiology, University of Illinois College of Medicine in Chicago.
Bromadiolone may cause severe acute kidney injury through severe disorder of coagulation: a case report.
BMC Nephrol
September 2024
Department of Nephrology, Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.
Article Synopsis
- Bromadiolone is a long-acting anticoagulant rodenticide that can lead to serious coagulation issues, but cases of acute kidney injury (AKI) due to its poisoning haven't been reported until now.
- A 27-year-old woman developed severe coagulopathy and AKI after bromadiolone exposure, indicating a vitamin K deficiency; her kidney function worsened but later fully recovered with treatment.
- This case highlights that bromadiolone can cause AKI through severe coagulation dysfunction, which can be treated effectively with high doses of vitamin K and plasma transfusion.
Widespread use of anticoagulant rodenticides in agricultural and urban environments. A menace to the viability of the endangered Bonelli's eagle (Aquila fasciata) populations.
Environ Pollut
October 2024
Service of Toxicology and Forensic Veterinary Medicine, Department of Health Sciences, Faculty of Veterinary Medicine, Campus de Espinardo, Universidad de Murcia, 30100, Murcia, Spain; Toxicology and Risk Assessment Research Group, IMIB-Pascual Parrilla, University of Murcia, 30120 El Palmar, Spain.
Article Synopsis
- * A study analyzed 17 Bonelli's eagle carcasses in Eastern Spain, finding that all had been exposed to at least 5 of the 10 ARs tested, with second generation ARs being the most common.
- * The significant presence of ARs in these eagles, along with liver concentrations suggesting potential poisoning, raises concerns about their impact on the eagle population and associated risks to public health due to the diet of these birds.
Exposure to anticoagulant rodenticides in steppe polecat (Mustela eversmanii) and European polecat (Mustela putorius) in central Europe.
Sci Total Environ
October 2024
HUN-REN Balaton Limnological Research Institute, Klebelsberg Kunó utca 3, 8237 Tihany, Hungary; Institute of Animal Science, Hungarian University of Agriculture and Life Sciences, Guba Sándor út 40, 7400 Kaposvár, Hungary. Electronic address:
Article Synopsis
- Coumarin-type anticoagulant rodenticides (ARs) are widely used to control rodents, but they pose significant threats to predatory animals through both lethal and sublethal effects.
- A study conducted in Hungary from 2005 to 2021 found AR residues in 53% of steppe polecats and 39% of European polecats, with higher concentrations in steppe polecats and a diverse array of compounds in European polecats.
- Findings indicate that AR accumulation correlates with human population density and negatively with natural habitats, highlighting a pressing issue of secondary poisoning in food webs and the need for improved pesticide management for wildlife safety.
Silent Bird Poisoning in Poland: Reconfirmation of Bromadiolone and Warfarin as the Proximal Causes Using GC-MS/MS-Based Methodology for Forensic Investigations.
Pharmaceuticals (Basel)
June 2024
Department of Regulatory and Forensic Toxicology, Institute of Medical Expertises, ul. Aleksandrowska 67/93, 91-205 Łódź, Poland.
The extensive use of rodenticides poses a severe threat to non-target species, particularly birds of prey and scavengers. In this study, a GC-MS/MS-based method was used to unlock the cause of bird deaths in Poland. Organs (liver, heart, kidney, and lungs) collected during autopsies of two rooks () and one carrion crow (), as well as fecal samples, were analyzed for the presence of anticoagulant coumarin derivatives, i.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!