Reducing Confusion over the Microbiome.

Anal Chem

Department of Chemistry and Biochemistry, University of California, Santa Cruz, 1156 High Street, Santa Cruz, California 95064, United States.

Published: November 2023

AI Article Synopsis

  • Genetic tools are enhancing our understanding of microbial community diversity and identity.
  • These tools help predict the chemical interactions between bacteria, fungi, and their host.
  • Recent advancements in microbiome research are primarily driven by improved techniques in mass spectrometry.

Article Abstract

As genetic tools continue to emerge and mature, more information is revealed about the identity and diversity of microbial community members. Genetic tools can also be used to make predictions about the chemistry that bacteria and fungi produce to function and communicate with one another and the host. Ongoing efforts to identify these products and link genetic information to microbiome chemistry rely on analytical tools. This tutorial highlights recent advancements in microbiome studies driven by techniques in mass spectrometry.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10841885PMC
http://dx.doi.org/10.1021/acs.analchem.3c02408DOI Listing

Publication Analysis

Top Keywords

genetic tools
8
reducing confusion
4
confusion microbiome
4
microbiome genetic
4
tools continue
4
continue emerge
4
emerge mature
4
mature revealed
4
revealed identity
4
identity diversity
4

Similar Publications

Dopamine (DA) plays important roles in various behaviors, including learning and motivation. Recently, THOC5 was identified as an important regulator in the development of dopaminergic neurons. However, how THOC5 is regulated has not been explored.

View Article and Find Full Text PDF

A Multiplex High-Resolution Melting (HRM) assay to differentiate Fusarium graminearum chemotypes.

Sci Rep

December 2024

Cereal Disease Laboratory, Agricultural Research Service, US Department of Agriculture, St. Paul, MN, 55108, USA.

Fusarium graminearum is a primary cause of Fusarium head blight (FHB) on wheat and barley. The fungus produces trichothecene mycotoxins that render grain unsuitable for food, feed, or malt. Isolates of F.

View Article and Find Full Text PDF

Analyzing bacterial networks and interactions in skin and gills of Sparus aurata with microalgae-based additive feeding.

Sci Rep

December 2024

Department of Microbiology, Faculty of Sciences, CEI·MAR-International Campus of Excellence in Marine Science, University of Malaga, Málaga, Spain.

The inclusion of microalgae in functional fish diets has a notable impact on the welfare, metabolism and physiology of the organism. The microbial communities associated with the fish are directly influenced by the host's diet, and further understanding the impact on mucosal microbiota is needed. This study aimed to analyze the microbiota associated with the skin and gills of Sparus aurata fed a diet containing 10% microalgae.

View Article and Find Full Text PDF

Methamphetamine use disorder has emerged as a significant public health concern globally. This study endeavors to elucidate the alterations in expression changes of miRNAs in the plasma of methamphetamine use disorder and elucidate the alterations in miRNA expression in the plasma of individuals with methamphetamine use disorder and investigate the relationship between these differentially expressed miRNAs and the disorder itself, cravings for methamphetamine, and associated mental disorders. Furthermore, the study seeks to clarify the expression of downstream target molecules of specific miRNAs in the plasma of methamphetamine use disorder, assess the diagnostic utility of these miRNAs and their target molecules, explore their potential as biomarkers, and identify potential targets for the diagnosis and treatment of methamphetamine use disorder.

View Article and Find Full Text PDF

The proximity ligation-based Hi-C and derivative methods are the mainstream tools to study genome-wide chromatin interactions. These methods often fragment the genome using enzymes functionally irrelevant to the interactions per se, restraining the efficiency in identifying structural features and the underlying regulatory elements. Here we present Footprint-C, which yields high-resolution chromatin contact maps built upon intact and genuine footprints protected by transcription factor (TF) binding.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!