Background: Medication discrepancies can occur in transitions of care because of a lack of communication between hospitals and community pharmacies. These discrepancies can lead to preventable adverse drug events (ADEs).
Aim: To investigate the effect of electronic transmission of the basic discharge medication report on unintentional medication discrepancies observed between this report and the 28-day post-discharge status in the community pharmacy.
Method: The study took place in a Dutch teaching hospital and 8 community pharmacies. A quality improvement study with a nonrandomized, historically controlled intervention design was performed. The intervention consisted of the electronic transmission of a basic discharge medication report to the community pharmacies. Unintentional medication discrepancies were identified by comparing the basic discharge medication report to the 28-day post-discharge medication record in community pharmacies. The main outcome measure was the proportion of drugs with one or more unintentional discrepancies compared between the historical control group and intervention group, using the chi-square test. Secondary outcome measure was the proportion of patients with one or more unintentional discrepancies.
Results: The participants used a total of 1078 drugs in the control group and 862 in the intervention group. The intervention significantly reduced the proportion of drugs with an unintentional discrepancy from 230 out of 1078 in the control group (21.3%) to 149 out of 862 drugs in the intervention group (17.3%; p = 0.025). At patient level, a non-significant increase was seen (62.4-78.8%; p = 0.41).
Conclusion: The electronic transmission of the basic discharge medication report reduced the proportion of drugs with an unintentional discrepancy after discharge, but not the proportion of patients.
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http://dx.doi.org/10.1007/s11096-023-01650-5 | DOI Listing |
J Hazard Mater
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Guangdong Key Laboratory of Environmental Catalysis and Health Risk Control, Guangdong Hong Kong-Macao Joint Laboratory for Contaminants Exposure and Health, Institute of Environmental Health and Pollution Control, Guangdong University of Technology, Guangzhou 510006, China; Guangzhou Key Laboratory Environmental Catalysis and Pollution Control, Guangdong Basic Research Center of Excellence for Ecological Security and Green Development, School of Environmental Science and Engineering, Guangdong University of Technology, Guangzhou 510006, China.
Combined pollution status of heavy metals (HMs) and polycyclic aromatic hydrocarbons (PAHs) from non-ferrous metal smelting (NFMS) industry is crucial but has not been explored. Herein, the co-distribution of HMs and PAHs in a NFMS wastewater treatment plant and the impacts on the receiving river were investigated. Cu, As, and Ni were found to be the characteristic HMs, while Acenaphthylene was the characteristic PAHs in the NFMS wastewater.
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CAS Key Laboratory of Coastal Environmental Processes and Ecological Remediation Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences Yantai China.
Estuaries are ecologically sensitive areas influenced by river regulation. Knowledge of how marine megabenthos responds to river regulation and artificial flooding events remains limited. The study aims to provide a comprehensive understanding of the impacts of river regulation on marine megabenthic fauna.
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Laboratory of Experimental Physiopathology, Graduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, Criciuma, SC, Brazil; Hospital São José Research Center, Criciúma, SC, Brazil.
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January 2025
School of Materials Science and Engineering, Guangdong Provincial Key Laboratory of Advanced Energy Storage Materials, South China University of Technology, Guangzhou, 510640, China.
Ultrahigh-nickel layered oxide cathodes (≥90% nickel) possess exceptionally high discharge capacities, which can significantly improve the energy density of lithium-ion batteries and alleviate the driving range anxiety of electric vehicles. However, the high interfacial reactivity of ultrahigh-nickel cathodes, especially the detrimental side reactions with harmful acidic species like HF in the electrolyte, can deteriorate the battery interface and reduce the cycle life, hindering their practical application. In this study, 3-isocyanatopropyltrimethoxysilane (PTTS-NCO) is introduced as the electrolyte additive, which can effectively scavenge the harmful acidic species in the electrolyte and form a protective surface layer at the electrode/electrolyte interface, thereby enhancing the electrochemical performance of the battery (NCM90/Li).
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Department of Epidemiology and Statistics, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & School of Basic Medicine, Peking Union Medical College, Dongcheng District, Beijing, China.
Introduction: Frailty is thought to be associated with an increased risk of adverse health outcomes such as death and falls, but comparatively little is known about the impact of frailty transitions on the adverse health outcomes. Moreover, owing to insufficient sample size or a single-center study design, previous studies have not been sufficiently representative of elderly inpatients in China. This study aimed to provide estimates at the population level of the association between frailty transitions and adverse outcomes among elderly inpatients following discharge.
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