Multifunctional biological neural networks exploit multistability in order to perform multiple tasks without changing any network properties. Enabling artificial neural networks (ANNs) to obtain certain multistabilities in order to perform several tasks, where each task is related to a particular attractor in the network's state space, naturally has many benefits from a machine learning perspective. Given the association to multistability, in this paper, we explore how the relationship between different attractors influences the ability of a reservoir computer (RC), which is a dynamical system in the form of an ANN, to achieve multifunctionality. We construct the "seeing double" problem in order to systematically study how a RC reconstructs a coexistence of attractors when there is an overlap between them. As the amount of overlap increases, we discover that for multifunctionality to occur, there is a critical dependence on a suitable choice of the spectral radius for the RC's internal network connections. A bifurcation analysis reveals how multifunctionality emerges and is destroyed as the RC enters a chaotic regime that can lead to chaotic itinerancy.
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Sci Rep
January 2025
School of Mechanics and Engineering, Liaoning Technical University, Fuxin, 123000, China.
Uniaxial compression experiments were conducted on coal rock utilizing a computed tomography (CT) scanning system for real-time monitoring to explain the issue of gas volume significantly exceeding reservoir capacity during coal and gas outbursts. A percolation factor a which can make a significant contribution to the research on premonitory information of gas outbursts is introduced to determine whether percolation occurs in coal rock, and supports the outburst percolation theory. It was found that percolation probability and correlation length increase with greater porosity, and that the number of pore clusters decreases as porosity increases.
View Article and Find Full Text PDFCO flooding plays a crucial role in enhancing oil recovery and achieving carbon reduction targets, particularly in unconventional reservoirs with complex pore structures. The phase behavior of CO and hydrocarbons at different scales significantly affects oil recovery efficiency, yet its underlying mechanisms remain insufficiently understood. This study improves existing thermodynamic models by introducing Helmholtz free energy as a convergence criterion and incorporating adsorption effects in micro- and nano-scale pores.
View Article and Find Full Text PDFInt J Mol Sci
January 2025
MRL, Merck & Co., Inc., Rahway, NJ 07065, USA.
Despite the success of combination antiretroviral therapy (cART) to suppress HIV replication, HIV persists in a long-lived reservoir that can give rise to rebounding viremia upon cART cessation. The translationally active reservoir consists of HIV-infected cells that continue to produce viral proteins even in the presence of cART. These active reservoir cells are implicated in the resultant viremia upon cART cessation and likely contribute to chronic immune activation in people living with HIV (PLWH) on cART.
View Article and Find Full Text PDFCell
January 2025
Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 7610001, Israel. Electronic address:
Viruses encode proteins that inhibit host defenses, but sifting through the millions of available viral sequences for immune-modulatory proteins has been so far impractical. Here, we develop a process to systematically screen virus-encoded proteins for inhibitors that physically bind host immune proteins. Focusing on Thoeris and CBASS, bacterial defense systems that are the ancestors of eukaryotic Toll/interleukin-1 receptor (TIR) and cyclic GMP-AMP synthase (cGAS) immunity, we discover seven families of Thoeris and CBASS inhibitors, encompassing thousands of genes widespread in phages.
View Article and Find Full Text PDFEntropy (Basel)
January 2025
Chula Intelligent and Complex Systems Lab, Department of Physics, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand.
Quantum reservoir computing (QRC) has emerged as a promising paradigm for harnessing near-term quantum devices to tackle temporal machine learning tasks. Yet, identifying the mechanisms that underlie enhanced performance remains challenging, particularly in many-body open systems where nonlinear interactions and dissipation intertwine in complex ways. Here, we investigate a minimal model of a driven-dissipative quantum reservoir described by two coupled Kerr-nonlinear oscillators, an experimentally realizable platform that features controllable coupling, intrinsic nonlinearity, and tunable photon loss.
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