Background: This study aimed to investigate the impact of biochemical blood parameters on the progression of coronavirus disease (COVID-19). This retrospective study analyzed the clinical characteristics and biochemical test parameters of 352 COVID-19 patients treated at Malatya Training and Research Hospital in Turkey between March 3, 2021, and February 28, 2022.
Methods: The methodological approach of our study included specific analyses and examinations to assess the effect of biochemical blood values on disease progression in COVID-19 patients. To achieve this aim, blood samples were collected from patients and various biochemical tests were performed. The data obtained were evaluated using statistical analyses to examine the relationship between these specific biochemical blood values and the severity of COVID-19.
Results: High glucose, urea, alkaline phosphatase and lactate dehydrogenase levels and low albumin and potassium levels were associated with a more severe disease course. The results showed a significant link between certain biochemical blood values and the severity of COVID-19. These findings suggest that these markers may serve as valuable clinical indicators for predicting the disease progression and severity.
Conclusion: This study demonstrates the importance of monitoring and analyzing biochemical blood values as essential tools for assessing the severity and progression of COVID-19. The identified markers provide valuable information regarding the prognosis of the disease and may help healthcare professionals make informed decisions regarding patient care.
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http://dx.doi.org/10.1097/MD.0000000000035833 | DOI Listing |
PLOS Digit Health
January 2025
Clinical Care & Research, ORTEC B.V., Zoetermeer, The Netherlands.
Precision, or personalised medicine has advanced requirements for medical data management systems (MedDMSs). MedDMS for precision medicine should be able to process hundreds of parameters from multiple sites, be adaptable while remaining in sync at multiple locations, real-time syncing to analytics and be compliant with international privacy legislation. This paper describes the LogiqSuite software solution, aimed to support a precision medicine solution at the patient care (LogiqCare), research (LogiqScience) and data science (LogiqAnalytics) level.
View Article and Find Full Text PDFTrop Anim Health Prod
January 2025
Animal and Poultry Production Department, Faculty of Technology and Development, Zagazig University, Zagazig, 44519, Egypt.
The study investigates the effect of dietary herbal mixture (HM) levels on growing New Zealand White (NZW) rabbits' performance, carcass characteristics, blood biochemicals, and microbiological characteristics from 5 to 13 weeks of age. In this study, 96 New Zealand White rabbits (male and female ratio 1:1) were used, and they were five weeks old. The rabbits were at random allocated into four experimental groups (n = 24 each) comprising 12 replicates, each with two rabbits.
View Article and Find Full Text PDFBackground: Type 2 diabetes mellitus (T2DM) is among the modifiable risk factors for Alzheimer's disease (AD) and ranks among the leading chronic diseases globally. It is characterized by elevated blood glucose levels and insulin resistance, which over time may impair memory performance. More so, saliva appears to be a promising biomarker for the diagnosis of AD since conventional methods appear invasive and expensive in the country.
View Article and Find Full Text PDFBackground: Metabolic diseases like chronic Type 2 Diabetes Mellitus (T2DM) are now a serious global health concern In the United States. African Americans (AA) are being affected at a disproportionate rate with the condition compared to other ethnic groups, yet there are relatively few studies that have specifically focused on this group. Our previous findings have suggested that AA patients with T2DM had gene expression signals associated with Alzheimer's Disease (AD).
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Sistema Nacional de Investigación (SNI), Panamá, Panamá, Panama.
Background: We are conducting a biomarker-based study to describe the demographic and biomarker profiles of Panamanians. The objective of this report is to present the main findings on CSF, genetic and serological biomarkers' distribution and their association with cognition in a cohort of elderly people in Panama.
Method: Informed consent was applied to all participants, demographic data, medical history, and neuropsychological and functional status were collected, and non-fasting blood samples were obtained.
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