AI Article Synopsis
- The Chinese Visceral Adiposity Index (CVAI) is an important measure of fatty tissue dysfunction, and this study looks at how it relates to outcomes in Chinese patients who had ischemic strokes and underwent endovascular thrombectomy (EVT).
- Researchers found that among 453 patients, higher CVAI levels were linked to a greater chance of poor outcomes three months after treatment, with over half of the participants showing unfavorable results.
- The study concluded that CVAI could serve as a useful predictor for recovery in stroke patients, indicating that increased visceral fat correlates with worse outcomes post-EVT.
Article Abstract
Background And Purpose: The Chinese Visceral Adiposity Index (CVAI) is a reliable indicator of visceral adiposity dysfunction in the Chinese population. We aimed to evaluate the association between CVAI and clinical outcome in Chinese ischemic stroke patients who received endovascular thrombectomy (EVT).
Methods: This study retrospectively included patients with large vessel occlusive stroke receiving EVT treatment in 2 China stroke centers. Baseline CVAI was calculated after admission. Patients with a modified Rankin scale score ≥ 3 at 3 months after ischemic stroke were defined as poor outcome. Binary multivariate logistic regression models were utilized to explore the association between CVAI and the risk of 90-day unfavorable outcome.
Results: A total of 453 patients (mean age, 70.4 ± 12.1 years; 280 male) were included. During the 90-day follow-up, 236 (52.1 %) patients experienced poor outcome. After multivariable adjustment for potential confounders, increasing CVAI was associated with an increased risk of 90-day poor outcome (odds ratios, per-standard deviation increase: 1.521; 95 % confidence interval, 1.127-2.052; P = 0.006). Similar significant results were observed when the CVAI was analyzed as a categorical variable. Furthermore, the multiple-adjusted spline regression model showed an inverted J-shape association between CVAI and risk of unfavorable outcome (P = 0.048 for non-linearity).
Conclusions: This study demonstrated that CVAI is positively correlated with 90-day poor outcome in Chinese ischemic stroke patients after EVT.
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Source |
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| http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2023.107464 | DOI Listing |
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