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A Baffling Presentation of Metastatic Malignant Melanoma: Sporotrichoid Pattern Mimicking Vascular Tumor with Vitiligo-Like Depigmentation Following Immunotherapy.
Indian Dermatol Online J
May 2024
Department of Dermatology, Seth G.S. Medical College and KEM Hospital, Parel, Mumbai, Maharashtra, India.
Vitiligo-like hypopigmentation secondary to adjuvant checkpoint inhibitor therapy in patients with resectable stage III melanoma: a cohort from two tertiary hospitals.
Melanoma Res
January 2025
Department of Dermatology, Hospital Universitario y Politécnico La Fe.
Vitiligo-like hypopigmentation induced by immune checkpoint inhibitors (ICIs) has been largely associated with improved survival outcomes in metastatic melanoma. However, its development during adjuvant ICI therapy and its role as a prognostic factor in this setting remain unclear. We aimed to describe ICI-induced vitiligo in a cohort of patients with resected stage III melanoma treated with adjuvant ICI and to identify differences in progression-free survival (PFS) and distant metastasis-free survival (DMFS) between those who developed vitiligo and those who did not.
View Article and Find Full Text PDFImmune Checkpoint Inhibitor-Induced Vitiligo-Like Depigmentation.
JAMA Dermatol
December 2024
Oncodermatology Department, Institut Universitaire du Cancer, Toulouse Oncopole, Toulouse, France.
Early poliosis- and vitiligo-like depigmentation as an indicator of treatment response in patients with uveal melanoma under tebentafusp therapy.
Clin Exp Dermatol
October 2024
Department of Dermatology and Allergy, Skin Cancer Center, University Hospital Schleswig-Holstein, Campus Kiel, Germany.
Exploring the Genetic Landscape of Vitiligo in the Pura Raza Español Horse: A Genomic Perspective.
Animals (Basel)
August 2024
Departamento de Agronomía, Escuela Técnica Superior de Ingeniería Agronómica, Universidad de Sevilla, Ctra. Utrera Km 1, 41013 Sevilla, Spain.
Vitiligo is a depigmentation autoimmune disorder characterized by the progressive loss of melanocytes leading to the appearance of patchy depigmentation of the skin. The presence of vitiligo in horses is greater in those with grey coats. The aim of this study was therefore to perform a genome-wide association study (GWAS) to identify genomic regions and putative candidate loci associated with vitiligo depigmentation and susceptibility in the Pura Raza Español population.
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