AI Article Synopsis
- Exosomes are double-membrane vesicles that carry lipids, proteins, mRNAs, and non-coding RNAs, playing key roles in processes like cell communication and immune response.
- Research shows that the composition of exosomal proteins, nucleic acids, and lipids changes when host cells are infected.
- The study reviews existing literature on exosomes during infections and explores their potential as biomarkers for diagnosing and monitoring tuberculosis.
Article Abstract
Exosomes as double-membrane vesicles contain various contents of lipids, proteins, mRNAs and non-coding RNAs, and involve in multiple physiological processes, for instance intercellular communication and immunomodulation. Currently, numerous studies found that the components of exosomal proteins, nucleic acids or lipids released from host cells are altered following infection with . Exosomal contents provide excellent biomarkers for the auxiliary diagnosis, efficacy evaluation, and prognosis of tuberculosis. This study aimed to review the current literatures detailing the functions of exosomes in the procedure of infection, and determine the potential values of exosomes as biomarkers to assist in the diagnosis and monitoring of tuberculosis.
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Source |
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10622749 | PMC |
| http://dx.doi.org/10.3389/fimmu.2023.1254347 | DOI Listing |
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