AI Article Synopsis
- A 12-year-old boy exhibited symptoms of fever, a rash on his cheeks, back pain, and difficulty swallowing, prompting medical evaluation.
- Blood tests indicated high creatine kinase levels, and muscle ultrasound showed specific thickening in the back muscles, pointing towards muscle inflammation.
- A muscle biopsy confirmed dermatomyositis through specific proteins and antibodies, and treatment with prednisolone and immunoglobulin improved his symptoms and muscle condition.
Article Abstract
We herein report a 12-year-old boy who presented with a fever, erythematous rash on the cheeks, back pain, and dysphagia. Blood tests revealed increased creatine kinase levels, and muscle ultrasonography (MUS) revealed characteristic fascial thickening in the lumbar paraspinal muscles, where myalgia was prominent. Sarcoplasmic expression of myxovirus-resistant protein A on a muscle biopsy and the presence of anti-nuclear matrix protein 2 (NXP2) antibodies confirmed the diagnosis of dermatomyositis. Prednisolone and intravenous immunoglobulin therapy improved the clinical and laboratory parameters as well as fascial thickening. MUS is useful for evaluating fasciitis associated with anti-NXP2 autoantibodies and monitoring therapeutic efficacy.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11239255 | PMC |
| http://dx.doi.org/10.2169/internalmedicine.2720-23 | DOI Listing |
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