Fatigue and pain are prevalent in persons with multiple sclerosis (PwMS), negatively impacting quality of life (QoL). Clinical management is challenging due to their multiple underlying causes. Aerobic exercise elicits central and peripheral effects, which may effectively manage MS-related symptoms. Our aim was to determine the effects of an aerobic cycling intervention on symptoms impacting QoL. Eighteen participants completed a 12-week moderate- to high-intensity aerobic cycling intervention. Participants reported significant improvements in physical fatigue, overall fatigue, pain intensity, and pain interference. Aerobic exercise should be considered as part of a multi-faceted approach to improve fatigue and pain in PwMS.
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http://dx.doi.org/10.1016/j.msard.2023.105102 | DOI Listing |
Am J Physiol Heart Circ Physiol
January 2025
Neurovascular Research Laboratory, School of Kinesiology, Western University, London, Ontario, Canada.
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View Article and Find Full Text PDFMed Sci Sports Exerc
January 2025
Department of Zoology and Physiology, Program in Neuroscience, University of Wyoming, Laramie, WY.
Introduction: Circadian rhythms are responsible for physiological and behavioral processes coordinated in a 24-hour cycle. We investigated whether untimed, long-term voluntary wheel access mitigated circadian disruption and facilitated re-entrainment. Methods: Thirty-four C57Bl/6 J mice (n = 21 males, n = 14 females) were used in this experiment.
View Article and Find Full Text PDFEur J Appl Physiol
January 2025
Department of Kinesiology and Health Promotion, University of Kentucky, 1210 University Drive, Lexington, KY, 40526, USA.
Purpose: The purpose of this study was to examine the sex-specific influence of expected exercise duration on the physiological responses to RPE-clamp exercise anchored to RPE 15 with participants being deceived into believing the RPE-clamp exercise would last for 20-, 30-, or 40-min, but all trials were 30-min.
Methods: Twelve males and 12 females completed a graded exercise test followed by randomly ordered RPE-clamp trials at RPE15 on the Borg 6-20 scale where subjects were deceived into expecting exercise to last for either 20-, 30-, or 40-min, but the actual duration for each trial was 30-min. Separate 2 (Sex [Male vs.
Sci Rep
January 2025
Department of Physical Education, States University of Pará, Pará, Brazil.
It is well known that elite athletes of specific ethnicities and/or nationalities dominate certain sports disciplines (e.g., East Africans in marathon running).
View Article and Find Full Text PDFAndes Pediatr
August 2024
Departamento de Ciencias de la Actividad Física, Universidad Católica del Maule, Talca, Chile.
Unlabelled: Cardiorespiratory fitness can be assessed by direct, indirect, maximal, and moderate effort, running, cycling, or walking methods.
Objective: To predict maximum oxygen consumption (V O2max) from the six-minute walk test in schoolchildren.
Patients And Method: 459 students were included, 215 were male and 244 were female, aged 11.
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