AI Article Synopsis
Article Abstract
Outer tropical cyclone rainbands (TCRs) are a concentrated region of heavy precipitation and hazardous weather within tropical cyclones (TCs). Outer TCRs pose considerable risk to human societies, but their origin remains unresolved. Here, we identify a total of 1029 outer TCRs at their formative stage from 95 TCs and present a large collection of radar observations in order to establish a robust foundation of the natural diversity of rainband origin. The results show the dominance of outer origin for the observed outer TCRs, in distinct contrast to theoretical modeling works of outer TCRs, which propose inner-origin scenarios. Our analysis also suggests that squall-line dynamics are a common, but not the sole, mechanism responsible for outer TCR formation. The nature of preexisting outer precipitation is found to be an important factor to influence the squall-line and non-squall-line outer TCR initiation.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624872 | PMC |
| http://dx.doi.org/10.1038/s41467-023-42896-x | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Origin of outer tropical cyclone rainbands.
Nat Commun
November 2023
Department of Atmospheric Sciences, National Taiwan University, Taipei, Taiwan.
Outer tropical cyclone rainbands (TCRs) are a concentrated region of heavy precipitation and hazardous weather within tropical cyclones (TCs). Outer TCRs pose considerable risk to human societies, but their origin remains unresolved. Here, we identify a total of 1029 outer TCRs at their formative stage from 95 TCs and present a large collection of radar observations in order to establish a robust foundation of the natural diversity of rainband origin.
View Article and Find Full Text PDFCCR4 and CCR7 differentially regulate thymocyte localization with distinct outcomes for central tolerance.
Elife
June 2023
Department of Molecular Biosciences, The University of Texas at Austin, Austin, United States.
Central tolerance ensures autoreactive T cells are eliminated or diverted to the regulatory T cell lineage, thus preventing autoimmunity. To undergo central tolerance, thymocytes must enter the medulla to test their T-cell receptors (TCRs) for autoreactivity against the diverse self-antigens displayed by antigen-presenting cells (APCs). While CCR7 is known to promote thymocyte medullary entry and negative selection, our previous studies implicate CCR4 in these processes, raising the question of whether CCR4 and CCR7 play distinct or redundant roles in central tolerance.
View Article and Find Full Text PDFCD1 displays its own negative regulators.
Curr Opin Immunol
August 2023
Division of Rheumatology, Inflammation and Immunity, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 60 Fenwood Road, Boston, MA 02115, USA. Electronic address:
After two decades of the study of lipid antigens that activate CD1-restricted T cells, new studies show how autoreactive αβ T-cell receptors (TCRs) can directly recognize the outer surface of CD1 proteins in ways that are lipid-agnostic. Most recently, this lipid agnosticism has turned to negativity, with the discovery of natural CD1 ligands that dominantly negatively block autoreactive αβ TCR binding to CD1a and CD1d. This review highlights the basic differences between positive and negative regulation of cellular systems.
View Article and Find Full Text PDFT Cell Microvilli: Finger-Shaped External Structures Linked to the Fate of T Cells.
Immune Netw
February 2023
School of Life Sciences, Gwangju Institute of Science and Technology (GIST), Gwangju 61005, Korea.
Microvilli are outer membrane organelles that contain cross-linked filamentous actin. Unlike well-characterized epithelial microvilli, T-cell microvilli are dynamic similar to those of filopodia, which grow and shrink intermittently via the alternate actin-assembly and -disassembly. T-cell microvilli are specialized for sensing Ags on the surface of Ag-presenting cells (APCs).
View Article and Find Full Text PDFOuter Membrane Vesicles From The Gut Microbiome Contribute to Tumor Immunity by Eliciting Cross-Reactive T Cells.
Front Oncol
June 2022
Toscana Life Sciences Foundation, Siena, Italy.
A growing body of evidence supports the notion that the gut microbiome plays an important role in cancer immunity. However, the underpinning mechanisms remain to be fully elucidated. One attractive hypothesis envisages that among the T cells elicited by the plethora of microbiome proteins a few exist that incidentally recognize neo-epitopes arising from cancer mutations ("molecular mimicry (MM)" hypothesis).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!