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Is epigenome editing non-inheritable? Implications for ethics and the regulation of human applications. | LitMetric

Is epigenome editing non-inheritable? Implications for ethics and the regulation of human applications.

Stem Cell Reports

Graduate School of Humanities and Social Sciences, Hiroshima University, Hiroshima, Japan; Institute for the Advanced Study of Human Biology, Kyoto University, Kyoto, Japan; Centre for Biomedical Ethics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. Electronic address:

Published: November 2023

AI Article Synopsis

Article Abstract

Epigenome editing offers ethical advantages with non-inheritable gene expression control. However, concerns arise regarding potential transgenerational effects in humans. Ethical and regulatory evaluation is crucial, considering recent advancements and enhanced understanding of transgenerational epigenetics in both mammals and humans.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679648PMC
http://dx.doi.org/10.1016/j.stemcr.2023.10.003DOI Listing

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