Continuous generation of cross-linked polymer nanoparticles employing an ultrasonic microreactor.

In this article, a new system employing an ultrasonic microreactor coupled with a tubular reactor is presented for the continuous generation of polymer nanoparticles. The continuous generation of cross-linked polymer nanoparticles utilizing the monomer butyl methacrylate and the cross-linker ethylene glycol dimethacrylate is demonstrated. Firstly, the miniemulsion polymerization of a monomer-in-water miniemulsion is studied in a batch system. Secondly, a coiled tubular reactor is employed for the continuous polymerization of the miniemulsion generated by an ultrasonic microreactor. Finally, the influence of monomer volume fraction and surfactant concentration on the synthesized polymer nanoparticles is studied. Polymer particles in a size range of 50-250 nm are synthesized and a high polymerization conversion is achieved utilizing the system demonstrated in this article.