AI Article Synopsis
- Cefiderocol is a new antibiotic effective against hard-to-treat Gram-negative bacterial infections, with limited research involving children.
- In a case series, three immunocompromised children experienced harmless red or purple urine after receiving blood transfusions and cefiderocol.
- This discoloration may result from the interaction between cefiderocol and iron in blood products, so it's crucial to identify it properly to prevent unnecessary tests.
Article Abstract
Cefiderocol is a novel cephalosporin antibiotic with activity against multidrug-resistant Gram-negative bacteria and limited pediatric experience. This case series describes 3 immunocompromised children receiving blood transfusion who developed benign red or purple urine with administration of cefiderocol. Interaction with iron from blood products is a possible mechanism. It is important to recognize this phenomenon and distinguish it from hematuria to avoid unnecessary diagnostic testing.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/INF.0000000000004150 | DOI Listing |
Publication Analysis
Top Keywords
case series
8
cefiderocol red
4
red wine
4
wine urine
4
urine syndrome
4
syndrome pediatric
4
pediatric patients
4
patients multicenter
4
multicenter case
4
series cefiderocol
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!