AI Article Synopsis
- The burst-suppression pattern (BSP) is an EEG characteristic seen in conditions like coma, epilepsy in children, and can be produced by anesthesia or hypothermia, first noted in the literature in the late 1930s and formally named in 1949.
- Researchers have explored the relationship between the degree of EEG suppression and the effectiveness of seizure control in status epilepticus treatment, suggesting BSP might be a therapeutic target.
- However, historical evidence does not definitively support the effectiveness of inducing BSP for improving outcomes in patients experiencing refractory status epilepticus.
Article Abstract
After electroencephalography (EEG) was introduced in hospitals, early literature recognized burst-suppression pattern (BSP) as a distinctive EEG pattern characterized by intermittent high-power oscillations alternating with isoelectric periods in coma and epileptic encephalopathies of childhood or the pattern could be induced by general anesthesia and hypothermia. The term was introduced by Swank and Watson in 1949 but was initially described by Derbyshire et al. in 1936 in their study about the anesthetic effects of tribromoethanol. Once the EEG/BSP pattern emerged in the literature as therapeutic goal in refractory status epilepticus, researchers began exploring whether the depth of EEG suppression correlated with improved seizure control and clinical outcomes. We can conclude that, from a historical perspective, the evidence to suppress the brain to a BSP when treating status epilepticus is inconclusive.
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| http://dx.doi.org/10.1007/s12028-023-01877-0 | DOI Listing |
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