Integer Cystatin C Values: Impact on Discordance Group Assignment and Accuracy of GFR-Estimating Equations.

J Am Soc Nephrol

Division of Nephrology, Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

Published: November 2023

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635606PMC
http://dx.doi.org/10.1681/ASN.0000000000000184DOI Listing

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Background The 2020 Acute Disease Quality Initiative Consensus provided recommendations on novel acute kidney injury biomarkers. In this study, we sought to assess the added value of novel kidney biomarkers to a clinical score in the CASABLANCA (Catheter Sampled Blood Archive in Cardiovascular Diseases) study. Methods and Results We evaluated individuals undergoing coronary and/or peripheral angiography and added 4 candidate biomarkers for acute kidney injury (kidney injury molecule-1, interleukin-18, osteopontin, and cystatin C) to a previously described contrast-associated acute kidney injury (CA-AKI) risk score.

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