[The structural stability of negative symptoms over time].

BJPsych Open

Department of Psychiatry, University of Cambridge, Cambridge, UK; and Cambridge Psychosis Centre, Cambridgeshire and Peterborough NHS Foundation Trust, Cambridge, UK.

Published: November 2023

Negative symptoms remain poorly understood and treated despite their huge impact on patients' lives and clinical outcomes. This is partly because of ongoing debates about the clinical constructs underlying negative symptoms. A longitudinal analysis of the structure of negative symptoms presented in reports striking temporal stability of symptom structure, which behaves as a few independent domains. This further underscores the need to address specific symptom domains when considering interventions or pathophysiology studies.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10753967PMC
http://dx.doi.org/10.1192/bjo.2023.600DOI Listing

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