Moving closer towards a comprehensive view of tumor biology and microarchitecture using spatial transcriptomics.

Nat Commun

Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, and Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, USA.

Published: November 2023

Spatial transcriptomic profiling of cancer has enabled spatial delineation of malignant transcriptional heterogeneity, intercellular communication, and organization of microanatomical structures within the tumor microenvironment. This technical breakthrough paves the way for the development of precision diagnostic methods and targeted therapies.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10622517PMC
http://dx.doi.org/10.1038/s41467-023-42960-6DOI Listing

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