Mediterranean climates are characterized by warm, dry summers and mild, rainy winters. Previous studies suggest that over the last 1.36 Myr, Mediterranean winter rainfalls were in phase with the African monsoon. Here we present a high-resolution terrestrial and marine dataset for the Marine Isotope Stage 17 interglacial (Middle Pleistocene) from Southern Italy, showing that precipitation rates and regimes in the central Mediterranean varied independently of the monsoon system. Specifically, events of extreme summer precipitation were promoted by increased regional insolation rates and/or extratropical cyclones, and their magnitude was further enhanced by the advection of cool and humid North Atlantic air during stadials. Our findings provide new information on the short- to mid-term natural hydroclimatic variability of the Mediterranean basin, and offer new critical insights on land-ocean interactions at the regional scale by complementing previous analyses on the displacement of storm tracks toward southern Europe.
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http://dx.doi.org/10.1038/s41598-023-45812-x | DOI Listing |
PLoS Negl Trop Dis
December 2024
Genômica Funcional de Parasitos, Instituto René Rachou-Oswaldo Cruz Foundation, Belo Horizonte, Minas Gerais, Brazil.
Background: Visceral leishmaniasis (VL) is an infectious parasitic disease caused by the species Leishmania (Leishmania) infantum in the Mediterranean Basin, the Middle East, Central Asia, South America, and Central America, and Leishmania (Leishmania) donovani in Asia and Africa. VL represents the most severe and systemic form of the disease and is fatal if left untreated. Vaccines based on chimeric or multiepitope antigens hold significant potential to induce a highly effective and long-lasting immune response against infections by these parasites.
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January 2025
Manipal Centre for Biotherapeutics Research, Manipal Academy of Higher Education, Karnataka Manipal, 576 104 India.
The microbiota-gut-brain axis is a pivotal medium of crosstalk between the central nervous system (CNS) and the gastrointestinal tract. It is an intricate network of synergistic molecular pathways that exert their effects far beyond their local vicinity and even affect the systemic functioning of the body. The current review explores the involvement of the gut-brain axis (GBA) in the functioning of the nervous system, with a special emphasis on the neurodegeneration, cognitive decline, and neuroinflammation that occur in Alzheimer's disease (AD) and Parkinson's disease (PD).
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December 2024
Department of Cardiology, Faculty of Medicine, Mersin University, Mersin, Turkiye.
Background/aim: The epidemiological data on heart failure (HF) vary between regions within the same country. We aimed to investigate the epidemiological data on HF in Türkiye across all age groups regarding seven geographical regions.
Materials And Methods: We included all patients from the Turkish population who received a first diagnosis of HF between January 1, 2016 and December 31, 2022, using ICD-10 codes from the National Electronic Healthcare Database.
Sci Rep
December 2024
Dipartimento di Medicina, Chirurgia e Farmacia, University of Sassari, Viale San Pietro 43, Sassari, 07100, Italy.
More than two decades ago, in the central-eastern region of the Mediterranean island of Sardinia, a mountain area was identified where the population displays exceptional longevity, especially among men (the Longevity Blue Zone, LBZ). This community was thoroughly investigated to understand the underlying causes of the phenomenon. The present study analyzed 11 genetic markers previously associated with increased survival in several long-lived populations.
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December 2024
Institute of Marine Sciences, National Research Council (CNR-ISMAR), Bologna, Italy.
Anthropogenic and climate factors are increasingly affecting the composition and functions of many marine biogenic reefs globally, leading to a decline in associated biodiversity and ecosystem services. Once dominant ecological component, modern oyster reefs in the Mediterranean and Black Sea and the Atlantic Ocean have already been profoundly altered by overharvesting, habitat loss and the introduction of alien species. Far less known are deep-water oyster reefs, which can however form substantial biogenic structures below 30 m depth.
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