Paolo Claudio M. de Gusmao, Jeff L. Waugh Seminars in Pediatric Neurology Volume 25, April 2018, Pages 42-53 Chorea is a symptom of a broad array of genetic, structural, and metabolic disorders. While chorea can result from systemic illness and damage to diverse brain structures, injury to the basal ganglia, especially the putamen or globus pallidus, appears to be a uniting features of these diverse neuropathologies. The timing of onset, rate of progression, and the associated neurological or systemic symptoms can often narrow the differential diagnosis to a few disorders. Recognizing the correct etiology for childhood chorea is critical, as numerous disorders in this category are potentially curable, or are remediable, with early treatment.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.spen.2023.101088 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Ultrarare Cause of Childhood Chorea: Celiac Disease.
J Child Neurol
December 2024
Department of Pediatric Neurology, Ankara Etlik City Hospital, Ankara, Turkey.
Introduction: Chorea, a movement disorder that commonly affects children, may be caused by various diseases with metabolic, structural, pharmacologic, or autoimmune origins. Celiac disease is an autoimmune enteropathy that may rarely cause neurologic symptoms in children, primarily ataxia and peripheral neuropathy, even in the absence of gastrointestinal symptoms.
Case Report: A 9-year-old male patient diagnosed with Sydenham chorea was admitted to our clinic because of valproic acid resistance.
Bilateral deep brain stimulation (DBS) of globus pallidus internus (GPi) for the treatment of benign hereditary chorea and other childhood onset choreas: a single-center experience.
Neurosurg Rev
November 2024
Department of Neurosurgery, Alder Hey Children's NHS Foundation Trust, Eaton Road, Liverpool, L12 2AP, UK.
Purpose: Chorea is a clinical sign characterized by involuntary, rapid, unpredictable, and irregular muscle movements that can affect various parts of the body. It can be seen in various medical conditions, both neurological and systemic, of genetic and acquired etiology. Deep brain stimulation (DBS) of the globus pallidus internus (GPi) has been used to treat various types of chorea.
View Article and Find Full Text PDFMedication Use and Treatment Indications in Huntington's Disease; Analyses from a Large Cohort.
Mov Disord Clin Pract
December 2024
Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands.
Background: Huntington's Disease is a rare neurodegenerative disorder in which appropriate medication management is essential. While many medications are prescribed based on expert knowledge, overviews of actual medication use in HD are sparse.
Objectives: We provide a detailed overview of medication use and associated indications across HD disease stages, considering sex and regional differences.
Management, treatment, and clinical approach of Sydenham's chorea in children: Italian survey on expert-based experience.
Eur J Paediatr Neurol
September 2024
Clinica Pediatrica, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Sydenham's chorea (SC), an autoimmune disorder affecting the central nervous system, is a pivotal diagnostic criterion for acute rheumatic fever. Primarily prevalent in childhood, especially in developing countries, SC manifests with involuntary movements and neuropsychiatric symptoms. Predominantly occurring between ages 5 and 15, with a female bias, SC may recur, particularly during pregnancy or estrogen use.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!