AI Article Synopsis

  • SGLT2 inhibitors are increasingly used for managing diabetes and have additional benefits for kidney function and heart health.
  • Despite their advantages, they can cause complications like euglycemic ketoacidosis, which is a serious condition.
  • In a reported case, a 47-year-old patient developed ketoacidosis after 5 years on SGLT2 therapy, and successful resolution was achieved using somatostatin alongside standard treatment.

Article Abstract

Currently, the use of SGLT2 inhibitors is becoming more widespread, both for their role in controlling diabetes, and for their pleiotropic effects on glomerular hyperfiltration and heart failure. Along with their positive effects, these drugs can lead to various complications, the most severe being euglycemic ketoacidosis. The clinical case we have reported precisely describes this potentially serious complication which occurred in a 47-year-old patient who had been on SGLT2 inhibitor therapy for 5 years. In the resolution of this case we used, in addition to standard therapy, the continuous infusion of somatostatin, resulting in a rapid resolution of ketoacidosis and an improvement in the clinical condition.

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