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Home Urine Dipstick Screening for Bladder and Kidney Cancer in High-Risk Populations in England: A Microsimulation Study of Long-Term Impact and Cost-Effectiveness.
Pharmacoeconomics
January 2025
Sheffield Centre for Health and Related Research (SCHARR), School of Medicine and Population Health, The University of Sheffield, Regent Court, 30 Regent Street, Sheffield, UK.
Background: Testing high-risk populations for non-visible haematuria may enable earlier detection of bladder cancer, potentially decreasing mortality. This research aimed to assess the cost-effectiveness of urine dipstick screening for bladder cancer in high-risk populations in England.
Methods: A microsimulation model developed in R software was calibrated to national incidence data by age, sex and stage, and validated against mortality data.
Is biparametric MRI a feasible option for detecting clinically significant prostate cancer?: A systematic review and meta-analysis.
Urol Oncol
January 2025
Research Department, Urovallarta Medical Center, Puerto Vallarta, Mexico.
Background: Multiparametric MRI (Mp-MRI) is a key tool to screen for Prostate Cancer (Pca) and Clinically Significant Prostate Cancer (CsPca). It primarily includes T2-Weighted imaging (T2w), diffusion-weighted imaging (DWI), and Dynamic Contrast-Enhanced imaging (DCE). Despite its improvements in CsPca screening, concerns about the cost-effectiveness of DCE persist due to its associated side effects, increased cost, longer acquisition time, and limitations in patients with poor kidney function.
View Article and Find Full Text PDFOut of sight, into the spotlight: Beyond the current state of science on per- and poly-fluoroalkyl substances in groundwater.
J Environ Manage
January 2025
Department of Earth and Environmental Studies, Montclair State University, Montclair, NJ, 07043, USA.
Per- and poly-fluoroalkyl substances (PFAS) have emerged as a silent menace, infiltrating groundwater systems worldwide. Many countries, preoccupied with tackling legacy pollutants, have inadvertently neglected the emerging threat of PFAS. This review provides an exhaustive analysis beyond the current state of knowledge and sustainable pathways vis-a-vis addressing PFAS in groundwater systems globally.
View Article and Find Full Text PDF3D Breast Scanning in Plastic Surgery Utilizing Free iPhone LiDAR Application: Evaluation, Potential, and Limitations.
Aesthet Surg J
January 2025
Department of Plastic and Reconstructive Surgery, Brussels University Hospital - Vrije Universiteit Brussel (VUB), Brussels, Belgium.
Background: Three-dimensional (3D) imaging enhances surgical planning and documentation in plastic surgery, but high costs limit accessibility. Mobile Light Detection and Ranging (LiDAR) technology offers a potential cost-effective alternative.
Objectives: To evaluate the accuracy and clinical utility of iPhone-based LiDAR scanning for breast measurements compared to traditional methods, and to establish standardized protocols for clinical implementation.
Cost-Effective Drug Testing: Analytical Methodology, Best Practices, and Clinical Utility.
J Appl Lab Med
January 2025
Department of Pathology and Laboratory Medicine, UC Davis Health, Sacramento, CA, United States.
Background: Drug overdose-related deaths continue to increase globally. Testing demands have likewise increased, prompting healthcare facilities to adopt a range of methods, from simple point-of-care immunoassays to comprehensive chromatographic and mass spectrometry-based techniques. Each of these testing methods has trade-offs related to cost, performance, speed, and convenience, requiring healthcare facilities to carefully determine the best options to meet their clinical needs.
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