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Microwave-assisted Lewis acid catalysis for one-step preparation of high-performance buckwheat peptide-based films: Efficacy, mechanism, and applications.
Food Chem
December 2024
College of Food Science and Engineering, Ningxia University, Yinchuan, China. Electronic address:
This study presents a novel method for the efficient preparation of peptide-based films through microwave-assisted Lewis acid catalysis (MALC) of buckwheat globulin (BG). The MALC process efficiently degraded BG into small molecular peptides (1.6-1.
View Article and Find Full Text PDFBreaking Barriers in Huntington's Disease Therapy: Focused Ultrasound for Targeted Drug Delivery.
Neurochem Res
January 2025
Diagnostic Radiology Department, National Cancer Institute, Misrata, Libya.
Huntington's disease (HD) is a progressive neurodegenerative disease resulting from a mutation in the huntingtin (HTT) gene and characterized by progressive motor dysfunction, cognitive decline, and psychiatric disturbances. Currently, no disease-modifying treatments are available. Recent research has developed therapeutic agents that may have the potential to directly target the disease pathology, such as gene silencing or clearing the mutant protein.
View Article and Find Full Text PDFCatalytic Deconstruction of Commercial and End-of-Life Polyurethane with Heterogeneous Hydrogenation Catalyst.
ChemSusChem
January 2025
Qingdao University, College of Chemistry and Chemical Engineering, 308 Ningxia Road, Qingdao, CHINA.
Polyurethane (PU), as a thermoset polymer, is extensively utilized in various applications, such as refrigerator foams, sponges, elastomers, shoes, etc. However, the recycling of post-consumed PU poses significant challenges due to its intricate and extensive crosslinking structures. Catalytic hydrogenation is one of the most effective methods for recycling PU waste, nevertheless, there is currently a lack for a hydrogenation catalyst that is both high-performing, recyclable, and cost-effective for breaking down post-consumed PU materials.
View Article and Find Full Text PDFThe Physical Activity at Work (PAW) Program in Thai Office Workers: Mixed Methods Process Evaluation Study.
JMIR Form Res
January 2025
Health Intervention and Technology Assessment Programme, Ministry of Public Health, Nonthaburi, Thailand.
Background: An increasing number of multicomponent workplace interventions are being developed to reduce sedentary time and promote physical activity among office workers. The Physical Activity at Work (PAW) trial was one of these interventions, but it yielded an inconclusive effect on sedentary time after 6 months, with a low uptake of movement breaks, the main intervention component.
Objective: This study investigates the factors contributing to the outcomes of the PAW cluster randomized trial.
Strategic Acyl Carrier Protein Engineering Enables Functional Type II Polyketide Synthase Reconstitution In Vitro.
ACS Chem Biol
January 2025
Department of Chemistry, Haverford College, Haverford, Pennsylvania 19041, United States.
Microbial polyketides represent a structurally diverse class of secondary metabolites with medicinally relevant properties. Aromatic polyketides are produced by type II polyketide synthase (PKS) systems, each minimally composed of a ketosynthase-chain length factor (KS-CLF) and a phosphopantetheinylated acyl carrier protein (-ACP). Although type II PKSs are found throughout the bacterial kingdom, and despite their importance to strategic bioengineering, type II PKSs have not been well-studied .
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