Dietary fibre is beneficial for human health, but dietary intakes are below recommended levels in most countries. Cereals are the major source of dietary fibre in Western diets, with bread providing about 20% of the daily intake in the United Kingdom. Despite the promotion of fibre-rich wholegrain products, white bread (which has a lower fibre content) remains dominant in many countries due to cultural preferences. Increasing the fibre content of white bread and other products made from white flour is therefore an attractive strategy for increasing fibre intake. This can be achieved by exploiting genetic variation in wheat without major effects on the processing quality or the consumer acceptability of products. Modelling data for food consumption in the United Kingdom shows that increasing the fibre content of white flour by 50% (from about 4% to 6% dry weight) and in wholegrain by 20% will increase total fibre intake by 1.04 g/day and 1.41 g/day in adult females and males, respectively. Furthermore, in vitro studies indicate that the increased fibre content of white bread should reduce the rate of starch digestion and glucose release in the human gastrointestinal tract.
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http://dx.doi.org/10.1111/nbu.12648 | DOI Listing |
Adv Sci (Weinh)
December 2024
Department of Ultrasound in Medicine, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, No. 600, Yishan Road, Shanghai, 200233, P. R. China.
Rapid thrombolysis is very important to reduce complications caused by vascular blockage. A promising approach for improving thrombolysis efficiency is utilizing the permanent magnetically actuated locomotion of nanorobots. However, the thrombolytic drug transportation efficiency is challenged by in-plane rotating locomotion and the insufficient drug penetration limits further improvement of thrombolysis.
View Article and Find Full Text PDFActa Ophthalmol
December 2024
Department of Ophthalmology and Optometry, Medical University of Vienna, Vienna, Austria.
Purpose: The relationship between retinal morphology, as assessed by optical coherence tomography (OCT), and retinal function in microperimetry (MP) has not been well studied, despite its increasing importance as an essential functional endpoint for clinical trials and emerging therapies in retinal diseases. Normative databases of healthy ageing eyes are largely missing from literature.
Methods: Healthy subjects above 50 years were examined using two MP devices, MP-3 (NIDEK) and MAIA (iCare).
Animal Model Exp Med
December 2024
GemPharmatech Chengdu Co., Ltd., Chengdu, China.
Background: The emerging incidence of pathogenic liver conditions is turning into a major concern for global health. Induction of pyroptosis in hepatocytes instigates cellular disintegration, which in turn liberates substantial quantities of pro-inflammatory intracellular substances, thereby accelerating the advancement of liver fibrosis. Consequently, directing therapeutic efforts towards inhibiting pyroptosis could potentially serve as an innovative approach in managing inflammation related chronic hepatic disorders.
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December 2024
Key Laboratory of Special Engineering Equipment Design and Intelligent Driving Technology, Guilin University of Aerospace Technology, Guilin, 541004, China.
This paper purposed to prepare poly (lactic acid)/continuous cotton thread (PLA /CCT) filaments by using prepreg method, and investigated the properties of PLA/CCT filament and their 3D printed composites. Firstly, a prepreg device was home-made to immerse CCT with PLA melts. The effects of the dragging speed and tensioning equipment on the quality of PLA/CCT filament was investigated.
View Article and Find Full Text PDFSci Rep
December 2024
Department of Mechanical and Industrial Engineering, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal, 576104, Karnataka, India.
Metal and polymer interface bonding significantly influences the mechanical performance of fiber metal laminates (FMLs). Therefore, the effect of surface treatments (mechanical abrasion, nitric acid etching, P2 etching, sulfuric acid anodizing (SAA), and electric discharge machine (EDM) texturing) carried on aluminum 2024-T3 alloy sheets was evaluated considering surface morphology, surface topography, and surface roughness. Further, the influence of surface treatments on interfacial adhesion strength and failure mode between the aluminum alloy and carbon fiber prepreg was investigated.
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