The complexity of the evolution of the permeability of coal is determined by the reservoir structure. Further, there exists an interaction between the fracture matrix, which further complicates changes in permeability. When the actual mining conditions of a coal mine are considered, a permeability model that considered the combined effects of stress, gas adsorption, and temperature was proposed. Subsequently, the model is verified by published test data. Based on the analysis of permeability, a calculation model of the slip coefficient that considered the combined effects of stress, gas adsorption, and temperature is proposed. With respect to this, any change in the slippage coefficient is only determined by the width of the fracture channel, which affected the flow of coal gas. In the process of a temperature increase, the slip coefficient tends to increase and the larger effective stress corresponds to a larger slip coefficient. In addition, under constant-temperature conditions, we also discuss the evolution of coal permeability and the variation of the coal gas slippage factor under different boundary conditions through the proposed model. This study aims to further the understanding of the seepage characteristics and slippage effects of coalbed methane, which would have a positive impact on the mining of coal.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601075PMC
http://dx.doi.org/10.1021/acsomega.3c05001DOI Listing

Publication Analysis

Top Keywords

combined effects
12
effects stress
12
stress gas
12
gas adsorption
12
adsorption temperature
12
slip coefficient
12
evolution coal
8
considered combined
8
temperature proposed
8
coal gas
8

Similar Publications

Catechol-derived polymers form stable coatings on a wide range of materials including challenging to coat low surface energy polymers. Whether modification of the coating polymer with fluorophilic or hydrophobic groups is a successful approach to further favor the coating of hydrophobic or fluorophilic surfaces with catechol-based polymers remains ambiguous. Herein, we report the effect of a series of catechol-derived polyglycerol (PG)-based coatings and monolayer coatings on the wettability of polytetrafluoroethylene (PTFE), polystyrene, and poly(methyl methacrylate) surfaces.

View Article and Find Full Text PDF

Background: Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal diseases. Although several chemotherapy regimens have been developed over the past decades, few targeted therapies have shown a significant improvement in overall survival, partly due to the identification of PDAC as a single disease.

Methods: Combining metabolomic analysis and immunohistochemistry staining with Oil Red O staining, analysis for the oxygen consumption rate and extracellular acidification rate, we stratified pancreatic cancer cells into two subtypes.

View Article and Find Full Text PDF

Introduction: What interventions effectively prevent postoperative stenosis following endoscopic resection (ER) of superficial esophageal cancer? This study aimed to identify effective interventions or combinations through a systematic review and network meta-analysis.

Methods: Six databases were systematically searched for eligible studies up to 30 April 2023, on interventions to prevent esophageal stenosis post-ER. Odds ratios (ORs) evaluated stenosis rate (primary outcome) and complications (secondary outcome), while mean differences (MD) evaluated endoscopic balloon dilatation (EBD) sessions post-stenosis.

View Article and Find Full Text PDF

Purpose: Receptor CUB-domain containing- protein 1 (CDCP1) was evaluated as a target for detection and treatment of breast cancer.

Experimental Design: CDCP1 expression was assessed immunohistochemically in tumors from 423 patients (119 triple-negative breast cancer (TNBC); 75 HER2+; 229 ER+/HER2- including 228 primary tumors, 229 lymph node and 47 distant metastases). Cell cytotoxicity induced in vitro by a CDCP1-targeting antibody-drug conjugate (ADC), consisting of the human/mouse chimeric antibody ch10D7 and the microtubule disruptor monomethyl auristatin E (MMAE), was quantified, including in combination with HER2-targeting ADC T-DM1.

View Article and Find Full Text PDF

Cholestasis is a multifactorial hepatobiliary disorder, characterized by obstruction of bile flow and accumulation of bile, which in turn causes damage to liver cells and other tissues. In severe cases, it can result in the development of life-threatening conditions, including cirrhosis and liver cancer. Paeoniflorin (PF) has been demonstrated to possess favourable therapeutic potential for the treatment of cholestasis.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!