Viral diseases are responsible for substantial morbidity and mortality and continue to be of great concern. To ensure better control of viral infections, I have been tackling the issue as a medical doctor, an academic researcher, and a public health officer. Especially, I have studied respiratory viruses, such as the influenza virus, from the perspectives of molecular virology, theoretical modeling, and field epidemiology. RNA biology and its involvement with viral life-cycle and pathogenicity are central topics of molecular study, while mathematical models of transmission dynamics and phylogenetics are major components of theoretical research. As a field epidemiologist, I work with public health authorities during viral disease outbreaks. I was deployed to West Africa for viral hemorrhagic fever outbreak responses as a WHO consultant, and I have served the Japanese Government as an advisor for COVID-19 countermeasures. I would like to integrate various approaches from clinical medicine to epidemiology, theoretical modeling, evolutionary biology, genetics, and molecular biology in my research. In that way, we could gain a more comprehensive understanding of viral diseases. I hope these findings will help ease the disease burden of viral infections around the world.
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http://dx.doi.org/10.2222/jsv.72.87 | DOI Listing |
Indian J Med Ethics
January 2025
Senior Resident, Department of Forensic Medicine and Toxicology, AIIMS Bilaspur, Himachal Pradesh 174037, INDIA.
Telemedicine technology plays a crucial role in addressing healthcare challenges, particularly in countries like India, by mitigating physician shortages, reducing patient burden and costs, and aiding in disease prevention. The term telemedicine, meaning "healing at a distance," was coined in 1970 [1]. It encompasses the use of electronic, communication, and information technologies to deliver healthcare services remotely.
View Article and Find Full Text PDFBiomed Res Int
January 2025
College of Agriculture and Veterinary Medicine, Jimma University, Jimma, Ethiopia.
Bovine viral diarrhea virus (BVDV) is an important pathogen affecting dairy cattle all over the world by causing significant economic losses due to reproductive and respiratory problems, immunosuppressive effects, increased risk of morbidity, and calf mortality. A cross-sectional study was conducted from February 2021 to August 2021 to determine the seroprevalence of bovine viral diarrhea (BVD) and identify risk factors associated with its occurrence in and around Nekemte Town of Ethiopia. Blood samples were collected from 305 dairy cattle of 41 herds by using cluster-sampling method.
View Article and Find Full Text PDFWorld J Gastrointest Oncol
January 2025
Institute of Liver Diseases, Institute of Translational Medicine, The First Hospital of Jilin University, Changchun 130061, Jilin Province, China.
In this editorial, we comment on the article by Mu , published in the recent issue of the . We pay special attention to the immune tolerance mechanism caused by hepatitis B virus (HBV) infection, the pathogenesis of hepatocellular carcinoma (HCC), and the role of antiviral therapy in treating HCC related to HBV infection. HBV infection leads to systemic innate immune tolerance by directly inhibiting pattern recognition receptor recognition and antiviral signaling pathways, as well as by inhibiting the immune functions of macrophages, natural killer cells and dendritic cells.
View Article and Find Full Text PDFOpen Forum Infect Dis
January 2025
International Statistics and Epidemiology Group, London School of Hygiene and Tropical Medicine, London, UK.
Background: Herpes simplex virus type 2 (HSV2) is an important cofactor for HIV acquisition and transmission. Associations between the infections are reexamined in longitudinal data from an HIV prevention trial.
Methods: The HPTN 071 (PopART) trial evaluated a combination prevention intervention in 21 urban communities in Zambia and South Africa.
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