Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/acsbiomaterials.3c01535 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A multiplex method for rapidly identifying viral protease inhibitors.
Mol Syst Biol
January 2025
Department of Pathology and Cell Biology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, 10032, USA.
With current treatments addressing only a fraction of pathogens and new viral threats constantly evolving, there is a critical need to expand our existing therapeutic arsenal. To speed the rate of discovery and better prepare against future threats, we establish a high-throughput platform capable of screening compounds against 40 diverse viral proteases simultaneously. This multiplex approach is enabled by using cellular biosensors of viral protease activity combined with DNA-barcoding technology, as well as several design innovations that increase assay sensitivity and correct for plate-to-plate variation.
View Article and Find Full Text PDFKnowledge, Attitude, and Practices Regarding Leprosy Among Nurses Employed at a Tertiary Healthcare Centre in Central India: An Epidemiological Study.
Cureus
December 2024
Dermatology, All India Institute of Medical Sciences, Nagpur, Nagpur, IND.
Introduction: Leprosy is a common infectious disease in India that can lead to nerve damage and disability. There is a dearth of knowledge regarding leprosy not only among the general public but also among healthcare workers. This knowledge gap leads to the generation of stigma and delay in the detection of new cases.
View Article and Find Full Text PDFCorrection of meta-analysis after retraction of article on the effects of anti-androgens in polycystic ovary syndrome.
EClinicalMedicine
January 2025
Monash Centre for Health Research and Implementation (MCHRI), Monash University, Clayton, VIC, Australia.
[This corrects the article DOI: 10.1016/j.eclinm.
View Article and Find Full Text PDFNutrition Module: Addressing the Nutrition Education Gap in Undergraduate Medical Curricula via a Novel Approach.
Med Sci Educ
December 2024
Department of Neurology, Atrium Health Wake Forest Baptist Medical Center, Winston-Salem, NC USA.
Introduction: Despite the known importance of nutrition on health outcomes, most medical curricula do not dedicate sufficient time to nutrition topics. Many barriers prevent the successful integration of nutrition education into existing curricula.
Methods: We created an online nutrition module to educate students about foundational nutritional topics.
Comparison and calibration of MP2RAGE quantitative T1 values to multi-TI inversion recovery T1 values.
Magn Reson Imaging
January 2025
Department of Electrical and Computer Engineering, Vanderbilt University, Nashville, TN, United States; Department of Computer Science, Vanderbilt University, Nashville, TN, United States; Vanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, TN, United States; Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN, United States; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, United States.
While typical qualitative T1-weighted magnetic resonance images reflect scanner and protocol differences, quantitative T1 mapping aims to measure T1 independent of these effects. Changes in T1 in the brain reflect structural changes in brain tissue. Magnetization-prepared two rapid acquisition gradient echo (MP2RAGE) is an acquisition protocol that allows for efficient T1 mapping with a much lower scan time per slab compared to multi-TI inversion recovery (IR) protocols.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!