Multifunctional substitutes for bone tissue engineering have gained significant interest in recent years in the aim to address the clinical challenge of treating large bone defects resulting from surgical procedures. Sol-gel mesoporous bioactive glass nanoparticles (MBGNs) have emerged as a promising solution due to their high reactivity and versatility. The effect of calcium content on MBGNs textural properties is well known. However, the relationship between their composition, textural properties, and reactivity has not yet been thoroughly discussed in existing studies, leading to divergent conclusions. In this study, pristine and copper-doped binary MGBNs were synthesized by a modified Stöber method, using a cationic surfactant as pore-templating agent. An opposite evolution between calcium content (12-26 wt%) and specific surface area (909-208 m/g) was evidenced, while copper introduction (8.8 wt%) did not strongly affect the textural properties. In vitro bioactivity assessments conducted in simulated body fluid (SBF) revealed that the kinetics of hydroxyapatite (HAp) crystallization are mainly influenced by the specific surface area, while the composition primarily controls the quantity of calcium phosphate produced. The MBGNs exhibited a good bioactivity within 3 h, while Cu-MBGNs showed HAp crystallization after 48 h, along with a controlled copper release (up to 84 ppm at a concentration of 1 mg/mL). This comprehensive understanding of the interplay between composition, textural properties, and bioactivity, offers insights for the design of tailored MBGNs for bone tissue regeneration with additional biological and antibacterial effects.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10608725 | PMC |
| http://dx.doi.org/10.3390/ma16206690 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A complementary experimental and computational study on methanol adsorption isotherms of H-ZSM-5.
Phys Chem Chem Phys
January 2025
UK Catalysis Hub, Research Complex at Harwell, Science and Technology Facilities Council, Rutherford Appleton Laboratory, OX11 0FA, UK.
Methanol adsorption isotherms of fresh f-ZSM-5 and steamed s-ZSM-5 (Si/Al ≈ 40) are investigated experimentally at room temperature under equilibrium and by grand canonical Monte Carlo (GCMC) simulations with the aim of understanding the adsorption capacity, geometry and sites as a function of steam treatment (at 573 K for 24 h). Methanol adsorption energies calculated by GCMC are complemented by density functional theory (DFT) employing both periodic and quantum mechanics/molecular mechanics (QM/MM) techniques. Physical and textural properties of f-ZSM-5 and s-ZSM-5 are characterised by diffuse reflectance infrared Fourier transformed spectroscopy (DRIFTS) and N-physisorption, which form a basis to construct models for f-ZSM-5 and s-ZSM-5 to simulate methanol adsorption isotherms by GCMC.
View Article and Find Full Text PDFPredicting Color Development and Texture Changes in Tomatoes Treated With Hot Water and Exposed to High-Temperature Ethylene Using Support Vector Regression.
J Texture Stud
February 2025
Department of Mathematics, Aditya University, Surampalem, Andhra Pradesh, India.
This study investigated the impacts of hot water treatment (HWT) at 50°C or 25°C for 5 min and high-temperature ethylene (HTE) exposure at varying temperatures (20°C, 30°C, or 35°C) and durations (24, 48, or 72 h) on the postharvest quality and antioxidant properties of mature green tomatoes (MG). Color changes, physicochemical characteristics, antioxidant compounds, and overall antioxidant ability were assessed. HWT increased β-carotene levels and oxygen radical absorbance capacity (ORAC) while preserving color metrics, despite later HTE exposure.
View Article and Find Full Text PDFNanoscale Magnetic Ordering Dynamics in a High Curie Temperature Ferromagnet.
Nano Lett
January 2025
Materials Science and Technology Division, Oak Ridge National Laboratory, 1 Bethel Valley Rd, Oak Ridge, Tennessee 37831, United States.
Thermally driven transitions between ferromagnetic and paramagnetic phases are characterized by critical behavior with divergent susceptibilities, long-range correlations, and spin dynamics that can span kHz to GHz scales as the material approaches the critical temperature , but it has proven technically challenging to probe the relevant length and time scales with most conventional measurement techniques. In this study, we employ scanning nitrogen-vacancy center based magnetometry and relaxometry to reveal the critical behavior of a high- ferromagnetic oxide near its Curie temperature. Cluster analysis of the measured temperature-dependent nanoscale magnetic textures points to a 3D universality class with a correlation length that diverges near .
View Article and Find Full Text PDFUnlabelled: Sensory stimuli vary across a variety of dimensions, like contrast, orientation, or texture. The brain must rely on population representations to disentangle changes in one dimension from changes in another. To understand how the visual system might extract separable stimulus representations, we recorded multiunit neuronal responses to texture images varying along two dimensions: contrast, a property represented as early as the retina, and naturalistic statistical structure, a property that modulates neuronal responses in V2 and V4, but not in V1.
View Article and Find Full Text PDFRaisins are so popular in the human diet as a nutritional and sweet snack. The quality of this foodstuff depends on drying conditions. To minimize ochratoxin A (OTA) content and yeast and mold content (YMC) in raisins with favorable physicochemical and sensory properties, the response surface methodology (RSM) and the face-centered central composite design (FCCD) were utilized.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!