AI Article Synopsis
- - The study compared CT and MRI imaging techniques for staging liver metastases from colorectal and neuroendocrine tumors, using a data-driven approach to minimize bias in evaluating lesions.
- - In a sample of 76 patients, both imaging methods showed high agreement, but while they were similar in assessing colorectal liver metastases (CRLMs), MRI was found to be superior for neuroendocrine liver metastases (NELMs) in detecting more and smaller lesions.
- - The findings suggest that while CT and MRI are comparable for CRLMs, using MRI for NELMs could enhance treatment planning and surgical outcomes due to its increased detection capability.
Article Abstract
Background: We compared CT and MRI for staging metastatic colorectal or neuroendocrine liver metastases (CRLMs and NELMs, respectively) to assess their impact on tumor burden.
Methods: A prospectively maintained database was queried for patients who underwent both imaging modalities within 3 months, with two blinded radiologists (R1 and R2) independently assessing the images for liver lesions. To minimize recall bias, studies were grouped by modality, and were randomized and evaluated separately.
Results: Our query yielded 76 patients (42 CRLMs; 34 NELMs) with low interrater variability (intraclass correlation coefficients: CT = 0.941, MRI = 0.975). For CRLMs, there were no significant differences in lesion number or size between CT and MRI. However, in NELMs, Eovist-enhanced MRI detected more lesions (R1: 14.3 vs. 12.1, = 0.02; R2: 14.4 vs. 12.4, = 0.01) and smaller lesions (R1: 5.7 vs. 4.4, = 0.03; R2: 4.8 vs. 2.9, = 0.02) than CT.
Conclusions: CT and MRI are equivalent for CRLMs, but for NELMs, MRI outperforms CT in detecting more and smaller lesions, potentially influencing treatment planning and surgery.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605771 | PMC |
| http://dx.doi.org/10.3390/cancers15205109 | DOI Listing |
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