AI Article Synopsis
- The study investigates the use of an anti-reflux microcatheter during a treatment called DEB-TACE with DC Bead LUMI for patients with hepatocellular carcinoma (HCC).
- The results showed that the treatment was technically successful for all patients, but 55% had some residual disease after the procedure; over 45% showed no disease over a one-month follow-up.
- Safety was confirmed as there were no major complications, minor complications occurred in 10% of cases, and a high percentage of the tumor was covered by the beads in most cases (70%).
Article Abstract
Purpose: The present study aims to evaluate the effectiveness and safety of the anti-reflux microcatheter during DEB-TACE with DC Bead LUMI (radiopaque beads) for the treatment of hepatocellular carcinoma (HCC).
Methods: We performed an observational longitudinal prospective monocentric study to analyze all patients with HCC who underwent to DEB-TACE with DC Bead LUMI and anti-reflux microcatheter. Technical success, the presence of residual disease, and clinical success were evaluated. The performance of the anti-reflux microcatheter on the basis of the percentage of tumor covered and the non-target embolization (NTE) was also evaluated.
Results: Twenty patients underwent DEB-TACE with DC Bead LUMI and an anti-reflux microcatheter. Technical success was achieved in all cases. Residual disease in the target tumor was observed in 11/20 (55%) of cases and no residual disease was found in 9/20 (45%) of cases. The clinical response at 1-month follow-up was of PD 4/20 (20%), SD 7/20 (35%), and CR 9/20 (45%). No major complications were recorded, and 10% of cases had minor complications. The distribution of beads on post-procedural CBCT, classified according to the percentage of target nodule coverage, was ≥50% in 70% (14/20) of cases and between 30-50% in 30% of cases (6/20). NTE was never registered.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607252 | PMC |
| http://dx.doi.org/10.3390/jcm12206630 | DOI Listing |
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