Iturin: A Promising Cyclic Lipopeptide with Diverse Applications.

Biomolecules

The Pangenomics Lab, School of Science, RMIT University, Bundoora, VIC 3083, Australia.

Published: October 2023

AI Article Synopsis

  • This review focuses on iturin, a cyclic lipopeptide from bacteria, highlighting its diverse structures and strong antifungal properties, making it useful in bio-pesticides and medical treatments.
  • * Iturin is involved in various applications, including food emulsification, soil remediation, and enhancing oil recovery in petroleum, showcasing its versatility across different industries.
  • * The article emphasizes the importance of understanding iturin's structure and synthesis to unlock its potential antibacterial, antiviral, anticancer, and cosmetic uses as research on biosurfactants progresses.

Article Abstract

This comprehensive review examines iturin, a cyclic lipopeptide originating from and related bacteria. These compounds are structurally diverse and possess potent inhibitory effects against plant disease-causing bacteria and fungi. Notably, Iturin A exhibits strong antifungal properties and low toxicity, making it valuable for bio-pesticides and mycosis treatment. Emerging research reveals additional capabilities, including anticancer and hemolytic features. Iturin finds applications across industries. In food, iturin as a biosurfactant serves beyond surface tension reduction, enhancing emulsions and texture. Biosurfactants are significant in soil remediation, agriculture, wound healing, and sustainability. They also show promise in Microbial Enhanced Oil Recovery (MEOR) in the petroleum industry. The pharmaceutical and cosmetic industries recognize iturin's diverse properties, such as antibacterial, antifungal, antiviral, anticancer, and anti-obesity effects. Cosmetic applications span emulsification, anti-wrinkle, and antibacterial use. Understanding iturin's structure, synthesis, and applications gains importance as biosurfactant and lipopeptide research advances. This review focuses on emphasizing iturin's structural characteristics, production methods, biological effects, and applications across industries. It probes iturin's antibacterial, antifungal potential, antiviral efficacy, and cancer treatment capabilities. It explores diverse applications in food, petroleum, pharmaceuticals, and cosmetics, considering recent developments, challenges, and prospects.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604914PMC
http://dx.doi.org/10.3390/biom13101515DOI Listing

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