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Pharmacological coronary spasm provocative testing in clinical practice: A French Coronary Atheroma and Interventional Cardiology Group (GACI) position paper. | LitMetric

AI Article Synopsis

  • * Despite its prevalence, vasospastic angina is often underdiagnosed, and specific tests to identify it are not frequently conducted due to inconsistent protocols.
  • * The French Coronary Atheroma and Interventional Cardiology Group (GACI) released a position paper focusing on the criteria and protocols for conducting provocative tests to better diagnose and understand vasospastic angina.

Article Abstract

Vasospastic angina, also described as Prinzmetal angina, was first described as a variant form of angina at rest with transient ST-segment elevation; it is common and present in many clinical scenarios, including chronic and acute coronary syndromes, sudden cardiac death, arrhythmia and syncope. However, vasospastic angina remains underdiagnosed, and provocative tests are rarely performed. The gold-standard diagnostic approach uses invasive coronary angiography to induce coronary spasm using ergonovine, methylergonovine or acetylcholine as provocative stimuli. The lack of uniform protocol decreases the use and performance of these tests, accounting for vasospastic angina underestimation. This position paper from the French Coronary Atheroma and Interventional Cardiology Group (GACI) aims to review the indications for provocative tests, the testing conditions, drug protocols and positivity criteria.

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Source
http://dx.doi.org/10.1016/j.acvd.2023.10.002DOI Listing

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