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Localized Pigmented Villonodular Synovitis in the Shoulder: Report of a Case Treated through Arthroscopy.
Rev Bras Ortop (Sao Paulo)
November 2024
Serviço de Ortopedia e Traumatologia, Hospital Santa Rita de Cássia, Vitória, ES, Brasil.
Pigmented villonodular synovitis (PVNS) is rare in the shoulder, with few descriptions in the literature. We present the case of a 58-year-old female patient with no history of trauma. The patient reported pain for 2 months with no limb irradiation and presented lifting strength loss and progressive limitation of active and passive mobility.
View Article and Find Full Text PDFEmerging therapeutics in the management of tenosynovial giant cell tumor (TGCT).
Expert Rev Anticancer Ther
December 2024
Department of Internal Medicine, Division of Hematology/Oncology, University of Michigan, Ann Arbor, MI, USA.
Article Synopsis
- Tenosynovial giant cell tumors (TGCTs) are aggressive tumors often found in younger individuals, leading to long-term disability and typically managed via surgery, which has its own risks.
- This review focuses on systemic treatment options, particularly for the diffuse subtype (DT-TGCT), and assesses recent advancements and the historical context of these therapies.
- Notable progress includes the development of CSF1 receptor-targeting therapies like pexidartinib, paving the way for further research on treatment effectiveness and optimizing patient outcomes.
Co-occurrence of Pigmented Villonodular Synovitis and Patellar Clunk Syndrome Following Total Knee Arthroplasty: A Case Report.
Cureus
November 2024
Orthopaedic Surgery, The University of Alabama at Birmingham, Birmingham, USA.
Pigmented villonodular synovitis (PVNS) is an uncommon hyperproliferative disease of the synovium presenting either as localized or a more aggressive diffuse form. Its occurrence following total knee arthroplasty (TKA) is rare, and its presentation alongside patellar clunk syndrome (PCS) has not been previously reported. We present a case of a 64-year-old female patient diagnosed with diffuse PVNS (D-PVNS) two and half years following TKA, co-occurring with PCS.
View Article and Find Full Text PDFSoft tissue mass resembling myxochondroid metaplasia in Achilles tendon.
Skeletal Radiol
December 2024
Department of Radiology, University of Pittsburgh, UPMC Montefiore, 200 Lothrop Street, Pittsburgh, PA, NE 538.3, 15213, USA.
The Achilles tendon is the strongest and largest tendon in the human body, composed of the distal confluence of the gastrocnemius and soleus muscles and may also include the plantaris longus tendons. Despite its tremendous strength, it is frequently injured. Soft tissue tumors or tumor-like conditions of Achilles tendon are much less common in comparison to traumatic and infectious/inflammatory lesions.
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