AI Article Synopsis
- * The structure of these compounds was determined using advanced spectroscopy techniques and their absolute configuration was confirmed through electronic circular dichroism calculations.
- * The compounds were tested for their effectiveness against specific cancer cell lines, showing moderate cytotoxicity with one compound having an IC value of 21.3 μM against HCT-8 cells.
Article Abstract
Two new furanone derivatives, byssochlanones A-B (-) were purified from the endophytic fungus sp. isolated from the wetland plant, . Their structures were elucidated on the basis of extensive spectroscopic analyses. Compounds - represented typical furanone analogues which are not common in natural products. The absolute configuration of compounds - were identified through quantum-chemical electronic circular dichroism (ECD) calculation compared with their experimental CD. In addition, compounds - were tested for their cytotoxic activities against HCT-8 and Hela cancer cell lines, and compound showed moderate activity against HCT-8 cells with IC value of 21.3 M.
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| http://dx.doi.org/10.1080/14786419.2023.2275269 | DOI Listing |
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