This systematic review and meta-analysis aimed to collate the infection rates of spp. in intermediate host snails and their distribution in Africa. The overall infectivity prevalences of , and are 52%, 8%, and 3%, respectively. The intermediate host snails native to Africa ( and ) have been examined more than the invasive . The studies included in the review ranged from 1999 to 2022. North Africa has the highest prevalence of , with an infection rate of 52%. The review reveals that naturally infected intermediate host snails (, , and ) are found in various regions of Africa. accounts for 22% (from three countries) of the studies included in the review and it was only found in the North African region with the highest overall infection rate of 52%. More studies on infection rate and distribution are needed to effectively control and prevent future transmissions.
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http://dx.doi.org/10.3390/tropicalmed8100467 | DOI Listing |
PLoS Negl Trop Dis
January 2025
School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
Lake Victoria is a well-known hot spot for intestinal schistosomiasis, caused by infection with the trematode Schistosoma mansoni. The snail intermediate hosts of this parasite are Biomphalaria snails, with Biomphalaria choanomphala being the predominant intermediate host within Lake Victoria. The prevalence of S.
View Article and Find Full Text PDFJ Virol
December 2024
Key Laboratory of Virology and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei, China.
Chikungunya virus (CHIKV), an enveloped positive-sense RNA virus, is a member of the alphaviruses and cause fever and arthralgia in humans. We performed genome-wide CRISPR/Cas9-based screens and identified Y-box binding protein 1 (YBX1) as an essential cellular factor for CHIKV. Deficiency of YBX1 inhibited CHIKV RNA replication and impaired virus production.
View Article and Find Full Text PDFPhytopathology
January 2025
LSU AgCenter, 302 Life Science Building, Baton Rouge, Louisiana, United States, 70803;
and are major pests of sweetpotato. The ability of to cause symptoms and reproduce on nematode-resistant cultivars threatens the sweetpotato industry. To evaluate the penetration, development, and reproduction of and on sweetpotato, a time-course study was conducted using the genotypes 'LA14-31' (resistant to and intermediate-resistant to ), 'LA18-100' (susceptible to and resistant to ), and 'LA19-65' (resistant to and susceptible to ), with 'Beauregard' (susceptible to both species) and 'Jewel' (resistant to and intermediate-resistant to ) as controls.
View Article and Find Full Text PDFMetab Eng
December 2024
Department of Molecular Science and Technology and Advanced College of Bio-convergence Engineering, Ajou University, Woncheon-dong, Yeongtong-gu, Suwon, 16499, Republic of Korea. Electronic address:
The growing depletion of petroleum resources and the increasing demand for sustainable alternatives have spurred advancements in microorganism-based biofactories. Among high-value compounds, carotenoids are widely sought after in pharmaceuticals, cosmetics, and nutrition, making them prime candidates for microbial production. In this study, we engineered an efficient biosynthetic pathway in Escherichia coli for the production of the C-carotenoid crocetin-dialdehyde.
View Article and Find Full Text PDFCell
December 2024
Schaller Research Groups, Department of Infectious Diseases, Virology, Heidelberg University, Heidelberg, Germany; BioQuant, Heidelberg University, Heidelberg, Germany. Electronic address:
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