AI Article Synopsis
- Duration of untreated illness (DUI) is a crucial factor affecting long-term prognosis in patients with obsessive-compulsive disorder (OCD), typically lasting between 87.5 to 94.5 months.
- A systematic review was conducted, analyzing 71 initially identified studies, with only eight studies meeting the inclusion criteria, showing DUI averages from 7.0 to 20.9 years.
- Findings indicate that a longer DUI correlates with poorer long-term outcomes in OCD, highlighting the need for promoting early interventions targeting OCD symptoms.
Article Abstract
: Duration of untreated illness (DUI)-defined as the time period between the onset of a mental disorder and its first adequate treatment-should influence patients' long-term prognosis and outcome. In patients with obsessive-compulsive disorder (OCD), DUI lasts on average from 87.5 up to 94.5 months, being significantly longer compared with data available from patients affected by other severe mental disorders, such as schizophrenia and bipolar disorder. We carried out a systematic review in order to assess the impact of DUI on long-term outcomes in OCD patients. : A systemic review has been implemented, searching from inception to April 2023; only papers written in English were included. : Seventy-one articles were initially identified; only eight papers were included in the review. The DUI ranged from 7.0 ± 8.5 to 20.9 ± 11.2 years. Patients reporting a longer DUI have a poor long-term outcome in terms of lower level of treatment response and greater symptom severity. : The present review confirms that longer DUI has a negative impact on the long-term outcome of patients with OCD. It should be useful to promote the dissemination of early interventions with a specific focus on OCD symptoms.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10608019 | PMC |
| http://dx.doi.org/10.3390/jpm13101453 | DOI Listing |
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