is a rare opportunistic fungal pathogen that can be isolated from various environmental sources, including soil and animal feces. Although infrequent, infections caused by can be severe in immunocompromised patients. Here, we present a case of a prosthetic joint infection (PJI) in a 74-year-old female patient caused by . The patient presented with left knee pain, and septic loosening of the left knee endoprosthesis was diagnosed. She underwent surgical revision with the implantation of an antibiotic spacer and microbiologic testing. The results came back positive for both and (which is found in only a fraction of a percent of PJIs). She was treated with oral antimicrobials for 3 months postoperatively. This case report vividly illustrates a clinical scenario that underscores the significance of rigorous microbiologic testing procedures, accurate pathogen identification, unwavering vigilance in testing protocols, and a cautious approach that avoids succumbing to the seductive simplicity of Occam's razor.
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http://dx.doi.org/10.3390/pathogens12101270 | DOI Listing |
JBJS Case Connect
January 2025
Department of Orthopaedic Surgery, Walter Reed National Military Medical Center, Bethesda, Maryland.
Case: A 57-year-old man, 5 years status post right patellofemoral arthroplasty (PFA) with a first-generation (1 G) inlay implant, presented with knee pain and decreased function in midflexion. Radiographs demonstrated minimal degenerative changes in the remainder of the knee. Considering this, he was not a candidate for conversion to total knee arthroplasty (TKA) and was converted to an onlay PFA with excellent pain relief, motion, and return to high demand activities.
View Article and Find Full Text PDFJ Orthop Surg Res
March 2025
Department of Bone and Joint Surgery, Beijing Luhe Hospital, Capital Medical University, 82# Xinhua South Road, Tongzhou District, Beijing, 101149, People's Republic of China.
Background: Kinematic alignment (KA) unicompartmental knee arthroplasty (UKA), which has not been widely adopted in clinical practice, aims to implant a more personalized and physiologically compatible mobile-bearing UKA prosthesis for the treatment of advanced single compartment knee osteoarthritis. KA UKA is anticipated to enhance patient satisfaction and decrease the revision rate following UKA. However, its quantified biomechanical indicators remain unclear.
View Article and Find Full Text PDFBMC Musculoskelet Disord
March 2025
Department of Orthopaedic Surgery, Graduate School of Medicine, Mie University, 2-174 Edobashi, Tsu, 514-8507, Mie, Japan.
Background: Bi-cruciate retaining (BCR) total knee arthroplasty (TKA) is considered to provide improved clinical function and kinematics compared with conventional TKA, but it is unclear which factors affect clinical outcomes after BCR TKA. This study aimed to investigate whether rotational alignment of the femoral and tibial components and rotational mismatch between the femoral and tibial components affected early clinical outcomes after BCR TKA, according to the 2011 version of the Knee Society Score (2011KSS).
Methods: This retrospective cohort study included 39 knees that underwent BCR TKA.
J Orthop Traumatol
March 2025
Cartiheal Ltd, Tel Aviv, Israel.
Background: The aim of the study was to provide a gender-based analysis of the results of a large, multi-centre randomized controlled trial (RCT) comparing a novel cell-free aragonite-based scaffold with the standard of care (i.e. debridement/microfractures) for the treatment of chondral/osteochondral defects in knees with or without concurrent osteoarthritis.
View Article and Find Full Text PDFSci Data
March 2025
HGN Lab for Bionic Engineering, Department of Mechanical Engineering and Robotics Center, University of Utah, 1495 E 100 S, Salt Lake City, UT, 84112, USA.
After above-knee amputation, the biological knee and ankle are replaced with prostheses. The mobility level of individuals with amputation is related, in part, to the functionality of their prostheses. To understand healthcare needs of amputees, as well as design new, more helpful prostheses, we need to understand the biomechanical effects of using current prosthetic devices.
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