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Fiber-Optic-Based System for High-Resolution Monitoring of Stretch in Excised Tissues. | LitMetric

Fiber-Optic-Based System for High-Resolution Monitoring of Stretch in Excised Tissues.

Biosensors (Basel)

Biomedical Signal Interpretation and Computational Simulation (BSICoS) Group, I3A Institute, IIS Aragón, University of Zaragoza, 50018 Zaragoza, Spain.

Published: September 2023

AI Article Synopsis

Article Abstract

Cardiovascular diseases cause a high number of deaths nowadays. To improve these statistics, new strategies to better understand the electrical and mechanical abnormalities underlying them are urgently required. This study focuses on the development of a sensor to measure tissue stretch in excised tissues, enabling improved knowledge of biomechanical properties and allowing greater control in real time. A system made of biocompatible materials is described, which is based on two cantilevered platforms that integrate an optical fiber inside them to quantify the amount of stretch the tissues are exposed to with a precision of μm. The operating principle of the sensor is based on the variation of the optical path with the movement of the platforms onto which the samples are fixed. The conducted tests highlight that this system, based on a simple topology and technology, is capable of achieving the desired purpose (a resolution of ∼1 μm), enabling the tissue to be bathed in any medium within the system.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605064PMC
http://dx.doi.org/10.3390/bios13100900DOI Listing

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