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http://dx.doi.org/10.1177/17449871231187041 | DOI Listing |
Int J Lang Commun Disord
January 2025
Division of Communication Sciences and Disorders, University of Cape Town, Rondebosch, South Africa.
Background: There is a global need for synthetic speech development in multiple languages and dialects, as many children who cannot communicate using their natural voice struggle to find synthetic voices on high-technology devices that match their age, social and linguistic background.
Aims: To document multiple stakeholders' perspectives surrounding the quality, acceptability and utility of newly created synthetic speech in three under-resourced South African languages, namely South African English, Afrikaans and isiXhosa.
Methods & Procedures: A mixed methods research design was selected.
Sensors (Basel)
December 2024
School of Air Traffic Management, Civil Aviation Flight University of China, Guanghan 618307, China.
To address the issue of safe, orderly, and efficient operation for unmanned vehicles within the apron area in the future, a hardware framework of aircraft-vehicle-airfield collaboration and a trajectory planning method for unmanned vehicles on the apron were proposed. As for the vehicle-airfield perspective, a collaboration mechanism between flight support tasks and unmanned vehicle departure movement was constructed. As for the latter, a control mechanism was established for the right-of-way control of the apron.
View Article and Find Full Text PDFCancers (Basel)
December 2024
Faculty of Pharmacy, University of Montreal, 2940 Chem. de Polytechnique, Montreal, QC H3T 1J4, Canada.
Background/objectives: Through phase III clinical trials, PARP inhibitors have demonstrated outcome improvements in mCRPC patients with alterations in BRCA1/2 genes who have progressed on a second-generation androgen receptor pathway inhibitor (ARPI). While improving outcomes, PARP inhibitors contribute to the ever-growing economic burden of PCa. The objective of this project is to evaluate the cost-effectiveness of PARP inhibitors (olaparib, rucaparib, or talazoparib) versus the SOC (docetaxel or androgen receptor pathway inhibitors (ARPI)) for previously progressed mCRPC patients with BRCA1/2 mutations from the Canadian healthcare system perspective.
View Article and Find Full Text PDFInt J Mol Sci
December 2024
Russian Research Institute of Farm Animal Genetics and Breeding-Branch of the L.K. Ernst Federal Research Center for Animal Husbandry, Pushkin, Saint-Petersburg 196625, Russia.
During all periods of male ontogenesis, physiological processes responsible for the correct functioning of reproductive organs and spermatogenesis are under the influence of various factors (neuro-humoral, genetic, and paratypical). Recently, the attention of researchers has increasingly turned to the study of epigenetic factors. In scientific publications, one can increasingly find references to the direct role of microRNAs, small non-coding RNAs involved in post-transcriptional regulation of gene expression, in the processes of development and functioning of reproductive organs.
View Article and Find Full Text PDFBMC Public Health
January 2025
School of Population and Public Health (SPPH), University of British Columbia (UBC), 2206 East Mall, Vancouver, BC, V6T 1Z3, Canada.
Background: Widespread digital transformation necessitates developing digital competencies for public health practice. Given work in 2024 to update Canada's public health core competencies, there are opportunities to consider digital competencies. In our previous research, we identified digital competency and training recommendations within the literature.
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