Distinguishing nondiabetic renal disease (NDKD) from diabetic nephropathy (DN) is of paramount importance in choosing treatment modalities and determining renal prognosis. Nearly 40% of the patients with diabetes are likely to have NDKD. We report a case of a patient with diabetes with a massive nephrotic range of proteinuria that was labeled as DN based on LM and IF, but paraffin IF confirmed the presence of masked MN.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593287PMC
http://dx.doi.org/10.4103/ijn.ijn_126_22DOI Listing

Publication Analysis

Top Keywords

diabetic nephrotic
4
nephrotic syndrome
4
syndrome case
4
case "masked"
4
"masked" membranous
4
membranous nephropathy
4
nephropathy case
4
case report
4
report distinguishing
4
distinguishing nondiabetic
4

Similar Publications

Background: Lupus podocytopathy (LP) is a non-immune complex-mediated glomerular lesion in systemic lupus erythematosus (SLE), characterized by the diffuse effacement of podocyte processes without immune complex deposition or with only mesangial immune complex deposition. LP is a rare cause of nephrotic syndrome in SLE patients with implications for prognosis and treatment.

Case Report: We present the case of a 28-year-old woman with a medical history of type 1 diabetes mellitus (T1DM) who presented with lower limb edema, dyspnea, hypercholesterolemia, with nephrotic range proteinuria, without acute kidney injury, and laboratory findings compatible with auto-immune hemolytic anemia.

View Article and Find Full Text PDF

Nephrotic syndrome (NS) represents a prevalent syndrome among various chronic kidney disease pathologies and is known for its higher severity and worse prognosis compared with chronic glomerulonephritis. Understanding its pathogenesis and identifying more effective treatment modalities have long been a concern of kidney specialists. With the introduction of the gut-kidney axis concept and the progress in omics technologies, alterations in the gut microbiota have been observed in primary and secondary NS.

View Article and Find Full Text PDF

Introduction: Kidney Disease Improving Global Outcomes guidelines indicate that glucocorticoids and immunosuppressants comprise the first therapeutic regimens after 4 to 6 months of treatment for high-risk primary membranous nephropathy (PMN). However, some patients cannot achieve complete or partial remission at 6 months. This study aimed to evaluate the efficacy of traditional immunotherapy combined with hydroxychloroquine (HCQ), a well-known immune regulator, in patients with PMN.

View Article and Find Full Text PDF

Cytomegalovirus (CMV) infection is an opportunistic disease in immunocompromised patients that may appear without symptoms, with constitutional symptoms, or as a tissue-invasive disease. infection often manifests with non-specific symptoms; however, it can lead to severe malabsorption and extraintestinal dissemination by accelerated autoinfection. The coinfection of CMV and has rarely been reported, particularly with solely severe gastrointestinal bleeding.

View Article and Find Full Text PDF

Hyperosmolar hyperglycemic syndrome (HHS) is a common complication of diabetes mellitus. The episodes of HHS have been reported in patients with no prior history of diabetes. However, these incidents have rarely been reported in the literature.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!