Size-specific dose estimates (SSDEs) are dose indices that account for differences in body shape in computed tomography (CT) scans, allowing the evaluation of approximate absorbed doses in any cross section that could not be obtained with the volume CT dose index (CTDI). When using automatic exposure control (AEC), CTDI is modulated in the body axis direction, but the value displayed after the examination is the mean CTDI for the entire scan, and it is expected that the SSDE value will change depending on which value is used in the calculation. In this study, using a human body phantom, we examined the influence of whether the mean CTDI or the modulation value for each slice is used to calculate the SSDE on local organ dose evaluation. A program to calculate water equivalent diameter according to the procedure in the American Association of Physicists in Medicine Report No. 220 was developed and compared. As a result, SSDE calculated using the mean CTDI (local-SSDE) overestimated organ doses in the lung region by 18%-56% compared with those calculated by a web system for evaluating CT exposure doses (WAZA-ARIv2, Japan). In contrast, local-SSDE, which was calculated using the modulated value of the CTDI, was able to estimate the organ dose with a relative error of 10%-13%. The average local-SSDE over the entire body axis direction was not significantly different between the two methods, regardless of which method was used for CTDI. If the mean CTDI is stored in the Digital Imaging and Communications in Medicine (DICOM) header tag (0018, 9345) of the CT image and the modulated CTDI value is not available for each slice, the calculated local SSDE will contain many errors and will not correctly reflect the organ doses at the scan region. In such cases, it is available to use the method of evaluating local organ doses by multiplying the SSDE, which is the average of the SSDE for the entire scan, by a factor for each organ.
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http://dx.doi.org/10.6009/jjrt.2023-1373 | DOI Listing |
Curr Cardiol Rev
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Department of Nutrition, Société Francophone de Nutrithérapie et de Nutrigénétique Appliquée, Villeurbanne, France.
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January 2025
Department of Radiology, College of Medicine, University of Florida, Gainesville, FL.
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Methods: We assessed the performance of two similar 320-detector CT scanners: one equipped with PVO and one without.
Synchrotron X-ray microtomography (S-µCT) is a highly valuable technique for investigating organ function and pathologies. However, its application is often limited by high radiation doses and the occurrence of ring artifacts. While S-µCT utilizing sparse-view projections can effectively decrease radiation doses, the reconstructed images frequently exhibit severe streaking artifacts, which are exacerbated by ring artifacts, ultimately compromising reconstruction accuracy, image quality, and resolution.
View Article and Find Full Text PDFVet Res
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Department of Fundamental Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, 61 Daizong Street, Tai'an, 271018, Shandong, China.
Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most harmful pathogens in the swine industry. Our previous studies demonstrated that the small extracellular domain (ECL2) of CLDN4 effectively blocks PRRSV infection. In this study, we explored the in vivo administration of swine ECL2 (sECL2) and found that it blocked HP-PRRSV infection and alleviated histopathological changes in organs.
View Article and Find Full Text PDFSci Rep
January 2025
Faculty of Computer and Information, South Valley University, Qena, 83523, Egypt.
Ra, Th, and K levels in various foods frequently consumed by Egyptians were determined using a gamma-ray spectrometer based on the germanium detector (HPGe). Activity concentrations of Ra, Th, and K were in the range of < 0.10 to 0.
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