Introduction: Responses to trauma are often characterized either by the presence or absence of psychological distress; however, the process of adapting after trauma also includes potential positive change. While some studies document that the majority of individuals exposed to single event terrorism report low levels of psychological distress, more research is needed to understand different adaptation profiles following this type of trauma, and the factors that might predict responses.
Methods: We examined post-trauma responses in 257 first responders/medical professionals (66.8 percent) and civilians (33.2 percent) exposed to the 2013 Boston Marathon Bombings. Data for post-trauma profiles-post-traumatic growth (PTG), post-traumatic stress, and emotion regulation-and profile predictors-trauma proximity, trauma history, and coping flexibility-were collected approximately 2.5 years after the bombings. Latent profile analysis identified response profiles, and multinomial logistic regression identified demographic, event-specific, and psychological predictors of profile membership.
Results: Four profiles emerged: (1) symptomatic, (2) resistant, (3) resilient, and (4) struggling growth. First responder role decreased the odds of belonging to the struggling growth profile, as compared to the symptomatic profile. Greater coping flexibility and adaptive emotion regulation increased the odds of membership in the struggling growth, rather than symptomatic profile.
Conclusion: A subset of individuals experiencing post-traumatic stress symptoms years after trauma exposure may also be utilizing flexible, adaptive coping strategies and experiencing PTG. First responders may have difficulty experiencing simultaneous -distress and growth, and interventions designed to promote healthy post-trauma adaptation for this population could be tailored accordingly.
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Front Genet
January 2025
Genetics and Personalized Medicine Clinic, Institute of Clinical Medicine, University of Tartu, Tartu, Estonia.
Introduction: related disorders (PRD, OMIM: *171834) are genetic disorders resulting from pathogenic somatic mosaic variants in the gene, which encodes a protein crucial for regulating cell growth and division. PRD typically manifest during the post-zygotic phase, leading to a broad spectrum of overgrowth and vascular malformations affecting various body regions.
Methods: Conventional diagnostic methods struggle to detect and confirm pathogenic PIK3CA gene variants due to the mosaic nature of these disorders and the limited accessibility of affected tissues.
Nanoscale
January 2025
Lawrence Livermore National Laboratory, 7000 East Ave, Livermore, CA 94550, USA.
Quantum dots (QDs) are promising materials for optoelectronic applications, but their widespread adoption requires controllable, selective, and scalable deposition methods. While traditional methods like spin coating and drop casting are suitable for small-scale deposition onto flat substrates, and ink-jet printing offers precision for small areas, these methods struggle with conformal deposition onto non-planar, large area substrates or selective deposition onto large area chips. Electrophoretic deposition (EPD) is an efficient and versatile technique capable of achieving conformal and selective area deposition over large areas, but its application to QD films has been limited.
View Article and Find Full Text PDFPerspect Med Educ
January 2025
Wenckebach Institute, Lifelong Learning, Education and Assessment Research Network (LEARN), University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands.
Background: Educators struggle to implement Interprofessional Education (IPE) in workplace settings. We adopted an educational design research (EDR) approach to implement an IPE activity and establish design principles supporting IPE implementation in workplace settings.
Method: We adopted an iterative process of analysis/exploration, design/construction and evaluation/reflection.
Int J Environ Res Public Health
January 2025
Pathfinder Pakistan, Khayaban-e-Jami, Block 9 Clifton, Karachi 75600, Sindh, Pakistan.
Pakistan is confronted with the formidable challenge of high population growth, which is compounded by cultural norms that prioritize male offspring, leading to adverse implications for family planning efforts and demographic trends. Despite efforts to promote contraception, including a national family planning program, Pakistan continues to struggle with low and stagnant contraceptive prevalence rates among married women. The influence of gender composition on modern contraceptive uptake remains underexplored, necessitating research to elucidate its impact on reproductive behavior.
View Article and Find Full Text PDFAdv Sci (Weinh)
January 2025
Data61, CSIRO, Clayton, VIC, 3168, Australia.
The rapid growth of Internet of Things (IoT) devices necessitates efficient data compression techniques to manage the vast amounts of data they generate. Chemiresistive sensor arrays (CSAs), a simple yet essential component in IoT systems, produce large datasets due to their simultaneous multi-sensor operations. Classical principal component analysis (cPCA), a widely used solution for dimensionality reduction, often struggles to preserve critical information in complex datasets.
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